MRI and 1H MRS evaluation for the serial bile duct changes in hamsters after infection with Opisthorchis viverrini

Hanpanich, Petcharakorn; Pinlaor, Somchai; Charoensuk, Lakhanawan; Yongvanit, Puangrat; Thomas, Chunpen; Kothan, S.; Mairiang, Eimorn

doi:10.1016/j.mri.2013.05.008

Cited by 10 publications

(19 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…At week 5, MRI showed progression of intrahepatic duct dilatation throughout the liver. The changes in the bile ducts were graded 1, 2, and 3 at 1, 3 and 5 weeks p.i, respectively, which were essentially the same as those seen in our previous study on O. viverrini infection alone (OV group) [29].…”

Section: Mri Studysupporting

confidence: 76%

“…Comparison between the ON group in this study and the OV group in the previous study [29] revealed that periductal fibrosis and dilatation in intra and extra-hepatic duct were much more severe in the ON group than in the OV group from 1 to 21 weeks p.i.…”

Section: Mri Studysupporting

confidence: 45%

“…Unlike previously studied in O. viverrini-infected hamsters alone [29], 20 death animals in the ON group after MRI investigation during 9-19 weeks p.i. were observed and included in the data analyses.…”

Section: Clinical Signs Of Animal Observationmentioning

confidence: 81%

“…We previously reported that MRI and 1 H MRS were useful in monitoring serial changes of periductal fibrosis in the liver of O. viverrini-infected hamsters [29], the differential diagnosis of CCA appearance from those previously reported is unclear. The purpose of this study is to describe a time profile of quantitative changes of the hepatobiliary structure in relation to CCA development using 3 T MRI and 1 H MRS in the liver of O. viverrini-infected and NDMA-treated hamsters.…”

Section: Introductionmentioning

confidence: 91%

“…Bile duct changes were graded 0 to 3, as follows: grade 0 for no high signal image intensity of bile ducts; grade 1 for high signal in one segment of the liver; grade 2 for high signal in two or three segments of the liver; and grade 3 for high signal in more than three segments of the liver [29]. MR images were read by two researchers, a scientist and a radiologist, who have more than 10 years of experience on the MRI diagnosis for human CCA with sufficient knowledge.…”

Section: Evaluation Of Mr Imagesmentioning

confidence: 99%

See 4 more Smart Citations

MRI and 1H MRS findings of hepatobilary changes and cholangiocarcinoma development in hamsters infected with Opisthorchis viverrini and treated with N-nitrosodimethylamine

Hanpanich

Pinlaor

Charoensuk

et al. 2015

Magnetic Resonance Imaging

Self Cite

View full text Add to dashboard Cite

Section: Mri Studysupporting

confidence: 76%

Section: Mri Studysupporting

confidence: 45%

Section: Clinical Signs Of Animal Observationmentioning

confidence: 81%

Section: Introductionmentioning

confidence: 91%

Section: Evaluation Of Mr Imagesmentioning

confidence: 99%

See 3 more Smart Citations

MRI and 1H MRS findings of hepatobilary changes and cholangiocarcinoma development in hamsters infected with Opisthorchis viverrini and treated with N-nitrosodimethylamine

Hanpanich

Pinlaor

Charoensuk

et al. 2015

Magnetic Resonance Imaging

Self Cite

View full text Add to dashboard Cite

Histological confirmation of periductal fibrosis from ultrasound diagnosis in cholangiocarcinoma patients

Chamadol

Pairojkul

Khuntikeo

et al. 2014

J Hepatobiliary Pancreat Sci

View full text Add to dashboard Cite

Cholangiocarcinoma (CCA) has no specific clinical signs and symptoms and non‐specific bio‐ and tumor‐markers in the early disease stage. Usually patients present to tertiary care with advanced disease stage. In order to detect early cases of CCA that may present as a mass, dilatation of intrahepatic duct or combination, ultrasonography is accepted as a powerful imaging tool. A smaller mass or bile duct segmental dilatation requires further imaging for characterization, including computerized tomography (CT) or magnetic resonance imaging (MRI). We examined whether liver echo pattern was correlated with high risk for CCA in an endemic area of Opisthorchis viverrini (Ov). Ov infestation caused chronic inflammation of the biliary tree by periductal fibrosis (PDF), which may subsequently lead to CCA development. In our study, a World Health Organization classification of pattern of increased periportal echo (IPE) for schistosomiasis was applied. Two CCA patients gave consent for operation. Histopathological diagnosis showed both had cholangiocarcinoma with periductal fibrosis of the non‐tumorous area of the liver. Ultrasonography was used to compare the non‐tumorous area with parenchymal echo pattern and was shown to have an early CCA detection role and a surveillance role in an endemic area of Ov by detection of PDF.

show abstract

In-vivo monitoring of development of cholangiocarcinoma induced with C. sinensis and N-nitrosodimethylamine in Syrian golen hamsters using ultrasonography and magnetic resonance imaging: a preliminary study

et al. 2016

View full text Add to dashboard Cite

show abstract

MRI and 1H MRS evaluation for the serial bile duct changes in hamsters after infection with Opisthorchis viverrini

Cited by 10 publications

References 41 publications

MRI and 1H MRS findings of hepatobilary changes and cholangiocarcinoma development in hamsters infected with Opisthorchis viverrini and treated with N-nitrosodimethylamine

MRI and 1H MRS findings of hepatobilary changes and cholangiocarcinoma development in hamsters infected with Opisthorchis viverrini and treated with N-nitrosodimethylamine

Histological confirmation of periductal fibrosis from ultrasound diagnosis in cholangiocarcinoma patients

In-vivo monitoring of development of cholangiocarcinoma induced with C. sinensis and N-nitrosodimethylamine in Syrian golen hamsters using ultrasonography and magnetic resonance imaging: a preliminary study

Contact Info

Product

Resources

About