MRI Features of Intramedullary Spinal Cord Ependymomas

Sun, Bo; Wang, Chung‐Cheng; Wang, James; Liu, Ali

doi:10.1177/1051228403257619

Cited by 16 publications

(27 citation statements)

References 10 publications

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“…90%–95% of these are glial tumours, the most common in adults being ependymoma (60%) 57. The MRI features of the most common types (ependymoma and astrocytoma) are lesions averaging three to four segments in length (range 1–10), with significant cord enlargement and variable contrast enhancement 58. They occur more commonly in the cervical and thoracic cord but there may be lumbar and conus involvement 58.…”

Section: Progressivementioning

confidence: 99%

“…The MRI features of the most common types (ependymoma and astrocytoma) are lesions averaging three to four segments in length (range 1–10), with significant cord enlargement and variable contrast enhancement 58. They occur more commonly in the cervical and thoracic cord but there may be lumbar and conus involvement 58. Up to 4% of patients with a demyelinating disorder or sarcoidosis are initially misdiagnosed as having a malignancy, based on the overlapping MRI features 59 60.…”

Section: Progressivementioning

confidence: 99%

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A practical approach to the diagnosis of spinal cord lesions

et al. 2018

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Every neurologist will be familiar with the patient with atypical spinal cord disease and the challenges of taking the diagnosis forward. This is predominantly because of the limited range of possible clinical and investigation findings making most individual features non-specific. The difficulty in obtaining a tissue diagnosis further contributes and patients are often treated empirically based on local prevalence and potential for reversibility. This article focuses on improving the diagnosis of adult non-traumatic, non-compressive spinal cord disorders. It is structured to start with the clinical presentation in order to be of practical use to the clinician. We aim, by combining the onset phenotype with the subsequent course, along with imaging and laboratory features, to improve the diagnostic process.

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Section: Progressivementioning

confidence: 99%

Section: Progressivementioning

confidence: 99%

A practical approach to the diagnosis of spinal cord lesions

et al. 2018

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“…Similarly, ependymomas are usually iso-intense on T1WI and hyperintense on T2WI, but the contrast enhancement is usually uniform 6. These are usually found solitary in the brain and spinal cord; however, a rare case of primary ependymomatosis has been reported involving multiple segments of the spinal cord without involvement of the brain 7.…”

Section: Discussionmentioning

confidence: 99%

Abscess or tumour? Lumbar spinal abscess mimicking a filum terminale tumour

Sajjad

Kaliaperumal²,

O’Sullivan³

2012

Case Reports

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SummaryA 62-year-old woman presented with a 4-month history of central lower backache and a 2-week history of progressive bilateral leg weakness. She also complained of numbness on her left thigh and gluteal region, associated with urinary hesitancy and constipation. On examination, she had bilateral partial foot drop, absent knee and ankle reflexes and a negative Babinski's reflex and associated hyperaesthesia in L3 distribution bilaterally with decreased anal tone. Laboratory results revealed normal inflammatory markers. MRI scan demonstrated a large uniformly enhancing lesion in the filum terminale suggestive of a lumbar spinal tumour. An emergency spinal laminectomy from L3 to S2 was performed. Per operatively, the duramater was thickened and hyperaemic. The histopathology report suggested inflammation with no evidence of malignancy. Tissue specimen of cultured Staphylococcus aureus was sensitive to flucloxacillin. A final diagnosis of lumbar spinal abscess was made and subsequent antibiotic treatment led to good clinical recovery.

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“…These tumors are usually glial in origin (90%) and the most common types are the ependymomas (60%) and astrocytomas (30%). [44][45][46] Astrocytomas Astrocytomas characteristically present as focal fusiform expansions in the spinal cord, commonly in the cervical and thoracic regions. 35,44 Ependymomas Fifty percent of all ependymomas will occur in the spine; half are intramedullary and half are located in the filum terminale.…”

Section: Intramedullary Tumorsmentioning

confidence: 99%