MRI features of spinal Fluorosis: Results of an endemic community screening

Ahmed, Iftekhar; Sohail, Saba; Hussain, Mushtaq; Khan, Nazeer; Khan, Muhammad Tassaduq

doi:10.12669/pjms.291.3200

Cited by 2 publications

(2 citation statements)

References 12 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…These formed the spectrum of magnetic resonances image findings in subjects with spinal flourosis having backache but no neurological findings. (Ahmed et al, 2013;Sang et al, 2010). The minimum risk level for fluoride intake is 0.05 mg / kg / day for chronic oral exposure (Choubisa, 2001).…”

Section: Bonementioning

confidence: 99%

Fluoride: Its Implications for Public Health

Alvarado¹,

Ceruelos²,

Juárez³

et al. 2018

Preprint

View full text Add to dashboard Cite

The use of fluoride (F-) for decreasing the prevalence and incidence of tooth decay was the greatest worldwide preventive public health measure of the 20th century. There have been controversial reports about the benefits of the use of F-, because in small amounts it helps prevent dental caries, but in high concentrations it can be potentially toxic and harmful to dental and systemic health. Since the mid-20th century, F- has been studied by toxicologists, looking at its deleterious effects in human populations. During the last decade, the interest on the undesirable effects has resurfaced because of the knowledge that it interacts with the cellular system, even in low doses, with a very small safety margin. Acute ingestion of toxic amounts of fluoride can cause corrosive gastric mucosa injury. Also respiratory effects such as bleeding, pulmonary edema, tracheostomy and shortness of breath, have been observed in individuals who inhale hydrogen fluoride. Some researchers had shown that F- is an oxidizing agent and a well-known reversible enzymatic inhibitor that interferes with the enzyme activity of at least 80 proteins, can altered the intracellular redox equilibrium, lipid peroxidation, as well as, alteration in the gene expression and apoptosis induction. The primary purpose of this review is to examine findings of the action of inorganic F-, and an overview of hard and soft tissue disturbances, known as fluorosis. The goal of this review is to enhance understanding of the mechanisms by which F- affects cells with an emphasis on human tissue-specific events.

show abstract

Section: Bonementioning

confidence: 99%

Fluoride: Its Implications for Public Health

Alvarado¹,

Ceruelos²,

Juárez³

et al. 2018

Preprint

View full text Add to dashboard Cite

show abstract

“…However, the literature search reveals scarcity of data on dental fluorosis. 17,18 prevalence and its characteristics in Thar district. Therefore we design a study to evaluate the fluoride estimation in drinking water and geometrical samples and to investigate the dental changes associated with increased fluoride intake that is the dental fluorosis in Thar.…”

Section: Introductionmentioning

confidence: 96%

Frequency of Dental Fluorosis in Population Drinking Water with High Fluoride Level in Thar

Ahmed¹,

Ali²,

Zaheer³

et al. 2020

J Pak Dent Assoc

Self Cite

View full text Add to dashboard Cite

OBJECTIVE: The objective of this study is to see the frequency of dental fluorosis in exposed area (Sammo Rind village of Thar District) and in unexposed area of Gadap town of Karachi and to find the association of fluoride level with dental fluorosis in both groups. METHODOLOGY: The water samples were taken from both the sites and fluoride estimation in water and geometrical, was determined using Fluoride Ion Selective Electrode (FISE) method. By random selection 121 subjects from Sammo Rind village and 121 controls from Gadap Town Karachi were included in study after informed consent. The participants were clinically examined by an expert university teacher dentist in proper dental setups in examination lights. RESULTS: A frequency of dental fluorosis of 100% was found among the study subjects with fluoride content as high as 6- 8 mg/dl as compared to prevalence of dental fluorosis 17.4% in unexposed group with water fluoride content as low as 0.30mg/dl. CONCLUSIONS: The high level of underground water fluoride level and cent per cent dental fluorosis in Thar area is an alarming situation that should be addressed immediately at national level. KEYWORDS: Exposed area, Dental Flurosis, Fluoride Level, Water Sample HOW TO CITE: Ahmed I, Ali A, Zaheer M, Fatima I, Khan N. Frequency of dental fluorosis in population drinking water with high fluoride level in Thar. J Pak Dent Assoc 2020;29(4):259-263. DOI: https://doi.org/10.25301/JPDA.294.259

show abstract

MRI features of spinal Fluorosis: Results of an endemic community screening

Cited by 2 publications

References 12 publications

Fluoride: Its Implications for Public Health

Fluoride: Its Implications for Public Health

Frequency of Dental Fluorosis in Population Drinking Water with High Fluoride Level in Thar

Contact Info

Product

Resources

About