Abstract:MRI has become the modality of choice for many diagnostic questions in musculoskeletal radiology. Naturally, with the increasing role of MRI in diagnosis of musculoskeletal conditions, clinicians have been eager to explore the possibility of using MR guidance for musculoskeletal procedures. Researchers are actively investigating the utility and practicality of MRI compared with more established modalities for procedure guidance such as computed tomography, fluoroscopy, and ultrasound. Early studies have demons… Show more
“…The added increments of CA were 0.5, 1, 1. 5,2,4,10,15,20,30,40, and 60 ll. To determine the amount of HA necessary for an adequate signal, we decreased the HA in 1-ml increments from 4 to 2 ml using CA concentrations of 1 and 4 ll/ml HA.…”
Section: Signal Evaluationmentioning
confidence: 99%
“…MRI-guided musculoskeletal interventions have been proven to be feasible [3]. The detection of soft tissues and other delicate structures, such as nerves, vessels, and spinal cord, improves the safety of these interventions [4]. Fast interventional MRI-sequences generate short repetition rates and allow real-time imaging during the intervention.…”
The aim of this study was to develop a signal-inducing bone cement for magnetic resonance imaging (MRI)-guided cementoplasty of the spine. This MRI cement would allow precise and controlled injection of cement into pathologic lesions of the bone. We mixed conventional polymethylmethacrylate bone cement (PMMA; 5 ml methylmethacrylate and 12 g polymethylmethacrylate) with hydroxyapatite (HA) bone substitute (2-4 ml) and a gadolinium-based contrast agent (CA; 0-60 μl). The contrast-to-noise ratio (CNR) of different CA doses was measured in an open 1.0-Tesla scanner for fast T1W Turbo-Spin-Echo (TSE) and T1W TSE pulse sequences to determine the highest signal. We simulated MRI-guided cementoplasty in cadaveric spines. Compressive strength of the cements was tested. The highest CNR was (1) 87.3 (SD 2.9) in fast T1W TSE for cements with 4 μl CA/ml HA (4 ml) and (2) 60.8 (SD 2.4) in T1W TSE for cements with 1 μl CA/ml HA (4 ml). MRI-guided cementoplasty in cadaveric spine was feasible. Compressive strength decreased with increasing amounts of HA from 46.7 MPa (2 ml HA) to 28.0 MPa (4 ml HA). An MRI-compatible cement based on PMMA, HA, and CA is feasible and clearly visible on MRI images. MRI-guided spinal cementoplasty using this cement would permit direct visualization of the cement, the pathologic process, and the anatomical surroundings.
“…The added increments of CA were 0.5, 1, 1. 5,2,4,10,15,20,30,40, and 60 ll. To determine the amount of HA necessary for an adequate signal, we decreased the HA in 1-ml increments from 4 to 2 ml using CA concentrations of 1 and 4 ll/ml HA.…”
Section: Signal Evaluationmentioning
confidence: 99%
“…MRI-guided musculoskeletal interventions have been proven to be feasible [3]. The detection of soft tissues and other delicate structures, such as nerves, vessels, and spinal cord, improves the safety of these interventions [4]. Fast interventional MRI-sequences generate short repetition rates and allow real-time imaging during the intervention.…”
The aim of this study was to develop a signal-inducing bone cement for magnetic resonance imaging (MRI)-guided cementoplasty of the spine. This MRI cement would allow precise and controlled injection of cement into pathologic lesions of the bone. We mixed conventional polymethylmethacrylate bone cement (PMMA; 5 ml methylmethacrylate and 12 g polymethylmethacrylate) with hydroxyapatite (HA) bone substitute (2-4 ml) and a gadolinium-based contrast agent (CA; 0-60 μl). The contrast-to-noise ratio (CNR) of different CA doses was measured in an open 1.0-Tesla scanner for fast T1W Turbo-Spin-Echo (TSE) and T1W TSE pulse sequences to determine the highest signal. We simulated MRI-guided cementoplasty in cadaveric spines. Compressive strength of the cements was tested. The highest CNR was (1) 87.3 (SD 2.9) in fast T1W TSE for cements with 4 μl CA/ml HA (4 ml) and (2) 60.8 (SD 2.4) in T1W TSE for cements with 1 μl CA/ml HA (4 ml). MRI-guided cementoplasty in cadaveric spine was feasible. Compressive strength decreased with increasing amounts of HA from 46.7 MPa (2 ml HA) to 28.0 MPa (4 ml HA). An MRI-compatible cement based on PMMA, HA, and CA is feasible and clearly visible on MRI images. MRI-guided spinal cementoplasty using this cement would permit direct visualization of the cement, the pathologic process, and the anatomical surroundings.
“…Elles constituent encore les principales indications, avec les interventions rachidiennes et les ablations tumorales. En ostéoarticulaire et en résection de tissus mous, l'IRMi a démontré une sécu-rité et des performances suffisantes pour être utilisée en routine clinique, comme le démontre le bref aperçu suivant [54].…”
Section: Quelques Exemples D'interventions Guidées Par Irmunclassified
“…MRI is especially useful for lesions that are difficult or impossible to visualize using other imaging modalities. 12 MRI is also useful in cases when it is impossible to obtain a biopsy result using other imaging guidance techniques. 12 Consequently, MRI is a potential imaging tool for guiding invasive procedures.…”
Section: Introductionmentioning
confidence: 98%
“…12 MRI is also useful in cases when it is impossible to obtain a biopsy result using other imaging guidance techniques. 12 Consequently, MRI is a potential imaging tool for guiding invasive procedures. In addition, MRI is radiation-free, which benefits both the physician and patient.…”
Biopsy under MRI guidance is especially valuable for the localization of bone marrow lesions, viable tumors (after chemotherapy or radiation), and lesions that cannot be visualized using CT. It is both accurate and safe, is a good alternative biopsy method, and may be a good adjunctive technique for the localization of bone lesions for radiofrequency ablation or other interventional procedures.
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