1992
DOI: 10.1111/j.1526-4610.1992.hed3210507.x
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MRI in Migraineurs

Abstract: Forty-six migraineurs and 69 age- and sex-matched controls referred for MRI scans of the brain were evaluated for the incidence of intracranial pathology. Axial long TR/short TE and long TR/long TE and sagittal short TR/short TE scans were performed in all patients. Enhancement with Gd-DTPA was performed in all controls and in nine migraineurs. Six of 46 (13%) of the migraineurs had white matter lesions versus three of 69 (4.3%) of the controls. The white matter lesions in migraineurs were seen in a younger ag… Show more

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Cited by 41 publications
(26 citation statements)
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“…Their pathological significance is not known, but they are frequently related to age and vascular risk factors. White matter hyperintensities have been linked to memory impairment, visuoconstructional and attentional difficulties, and deficiencies in abstract reasoning and speed of mental processing [43][44][45][46][47][48]. In our study, signal hyperintensities were related to both cognitive and psychiatric measures.…”
Section: Discussionmentioning
confidence: 42%
“…Their pathological significance is not known, but they are frequently related to age and vascular risk factors. White matter hyperintensities have been linked to memory impairment, visuoconstructional and attentional difficulties, and deficiencies in abstract reasoning and speed of mental processing [43][44][45][46][47][48]. In our study, signal hyperintensities were related to both cognitive and psychiatric measures.…”
Section: Discussionmentioning
confidence: 42%
“…2,8,[15][16][17][18][19][20][21][22][23] The populations in these studies were reasonably similar. Results from these studies were combined in a meta-analysis to yield a summary prevalence of 0.0018 (approximately 0.2%), with an upper 95% confidence limit of 0.0059 (approximately 0.6%).…”
Section: Nonacute Headache and Normal Neurological Examinationmentioning
confidence: 64%
“…Ischaemia or an immune-based white matter demyelinisation are other possible mechanisms for the white matter lesions [9].…”
Section: Migrainementioning
confidence: 99%