MRI in the diagnosis of testicular Leydig cell tumour

Fernández, Gabriel; Tardáguila, Francisco; Rivas, Celso; Trinidad, C; Pesqueira, Daniel; Zungri, E; Miguel, P. San

doi:10.1259/bjr/31653779

Cited by 28 publications

(16 citation statements)

References 13 publications

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“…At MR imaging, Leydig cell tumors have been described as isointense on T1-weighted and hypointense on T2-weighted images compared with the normal testis, with marked homogeneous enhancement, as in our case (Fig 9). In addition to these typical features, Leydig cell tumors can also demonstrate capsular high signal intensity on T2-weighted images and may have a high-signal-intensity central scar on T2-weighted images (30). Thus, the MR imaging appearance of Leydig cell tumors is not sufficiently specific to allow confident exclusion of alternative diagnoses, especially the far more common malignant germ cell tumors.…”

Section: Tumors With Malignant Potentialmentioning

confidence: 99%

MR Imaging of Scrotal Tumors and Pseudotumors

Cassidy¹,

Ishioka²,

McMahon³

et al. 2010

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Magnetic resonance (MR) imaging is an important imaging technique in the evaluation of scrotal masses, providing a useful adjunct to ultrasonography (US). Although US is the modality of choice for initial evaluation of scrotal pathologic conditions because of its wide availability, low cost, and high sensitivity for detection of testicular and paratesticular disease processes, US findings may occasionally be inconclusive. MR imaging may provide additional information in these cases, often affecting patient management. This article reviews and illustrates the MR imaging features of solid extratesticular and intratesticular benign and malignant scrotal tumors, as well as nonneoplastic lesions that can mimic neoplasia. Normal scrotal MR anatomic features and optimal MR imaging technique are also presented.

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Section: Tumors With Malignant Potentialmentioning

confidence: 99%

MR Imaging of Scrotal Tumors and Pseudotumors

Cassidy¹,

Ishioka²,

McMahon³

et al. 2010

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“…In addition, imaging characteristics argue also for this diagnosis. Indeed, as seen in our patient, LCTs are typically isointense on T1-weighted, -showed enhancement and are hypointense on T2 weighted with central areas of increased signal [23]. …”

Section: Discussionmentioning

confidence: 89%

Leydig Cell Tumor Associated with Testicular Adrenal Rest Tumors in a Patient with Congenital Adrenal Hyperplasia due to 11β-Hydroxylase Deficiency

Charfi

Kamoun

Mnif

et al. 2012

Case Reports in Urology

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Congenital adrenal hyperplasia (CAH) describes a group of inherited autosomal recessive disorders characterized by enzyme defects in the steroidogenic pathways that lead to the biosynthesis of cortisol, aldosterone, and androgens. Chronic excessive adrenocorticotropic hormone (ACTH) stimulation may result in hyperplasia of ACTH-sensitive tissues in adrenal glands and other sites such as the testes, causing testicular masses known as testicular adrenal rest tumors (TARTs). Leydig cell tumors (LCTs) are make up a very small number of all testicular tumors and can be difficult to distinguish from TARTs. This distinction is interesting because LCTs and TARTs require different therapeutic approaches. Hereby, we present an unusual case of a 19-year-old patient with CAH due to 11β-hydroxylase deficiency, who presented with TARTs and an epididymal Leydig cell tumor.

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“…Benign tumours are hyperechoic and homogeneous while malignant neoplasms can appear either homogeneously hypoechoic or have a heterogenous pattern involving hypoechoic and hyperechoic areas. Similar to LCTs, MRI has the potential to provide greater detail in terms of better defining the exact location of the neoplasm and how it relates to the different paratesticular structures, which might not be routinely possible with ultrasonography 11 12…”

Section: Discussionmentioning

confidence: 99%

One lump or two? Concomitant Leydig cell tumour and paratesticular leiomyoma in an adult man

et al. 2014

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SUMMARYWe present the first reported case of a concomitant Leydig cell tumour (LCT) and paratesticular leiomyoma in an adult man with a history of bilateral cryptorchidism. An 80-year-old man presented with a 2-month history of a left testicular lump associated with mild discomfort and a gradual increase in size on a background of bilateral cryptorchidism requiring multiple orchidopexy procedures as a child. Ultrasound confirmed a lesion suspicious for malignancy and he proceeded to a left radical orchidectomy. Histopathological assessment of the left testis revealed a concomitant testicular LCT with rare malignant features and paratesticular leiomyoma. BACKGROUND

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MRI in the diagnosis of testicular Leydig cell tumour

Cited by 28 publications

References 13 publications

MR Imaging of Scrotal Tumors and Pseudotumors

MR Imaging of Scrotal Tumors and Pseudotumors

Leydig Cell Tumor Associated with Testicular Adrenal Rest Tumors in a Patient with Congenital Adrenal Hyperplasia due to 11β-Hydroxylase Deficiency

One lump or two? Concomitant Leydig cell tumour and paratesticular leiomyoma in an adult man

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