MRI of primary amyloidosis

Rafal, Richard B.; Jennis, Richard; Kosovsky, Peter A.; Markísz, John A.

doi:10.1007/bf01888774

Cited by 30 publications

(9 citation statements)

References 7 publications

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“…Regarding MRI findings, they are similar to the ones described by Rafal et al [5]: They proved the enlargement of the pancreas on T1-weighted images and the increase on the pancreatic T2 values due to amyloid deposition in this gland; however, they do not comment on anything about its appearance on T1-weighted images that, in our case, showed decrease of signal.…”

Section: Discussionsupporting

confidence: 83%

“…We have only found radiological description of this glandular affectation with MRI [5] but not with US or CT; thus, we present our patient's findings whose pancreas demonstrated a pronounced enlargement in all imaging techniques, with totally hypoechoic appearance on US. It showed extensive and diffuse involvement due to hypodense material with solid attenuation values on helical CT together with loss of high signal on T1-and increased signal intensity on T2-weighted images.…”

Section: Discussionmentioning

confidence: 88%

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Pancreatic involvement in primary amyloidosis: radiologic findings

et al. 2001

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Amyloidosis is a rare disease that can involve a great variety of organs. As a consequence, clinical and radiological manifestations are very different as well. We report on a patient with primary amyloidosis who presented with diffuse pancreatic involvement detected by ultrasound, helical CT, and MRI. There are very few imaging descriptions about this glandular involvement in amyloidosis in the literature. Despite the apparent uncommon radiological appearance, we believe that this entity should be taken into account in the differential diagnosis of diffuse infiltrative pancreatic lesions in the appropriate clinical and analytical setting.

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Section: Discussionsupporting

confidence: 83%

Section: Discussionmentioning

confidence: 88%

Pancreatic involvement in primary amyloidosis: radiologic findings

et al. 2001

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“…Loss of hyperintense signal of pancreas parenchyma with primary amyloidosis on T1-weighted image was reported previously (5, 8). We observed same the same finding in our case (Fig.…”

Section: Discussionsupporting

confidence: 77%

Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas

et al. 2012

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A 39-year-old female patient presented to our hospital with epigastric pain lasting for two months. Laboratory results showed impaired glucose tolerance. Ultrasonography of the patient showed a hypoechoic, diffusely enlarged pancreas. CT revealed a large pancreas, with multiple calcifications. On MRI, a diffusely enlarged pancreas was seen hypointense on both T1- and T2-weighted images with heterogeneous enhancement after gadolinium administration. A biopsy of the pancreas revealed primary amyloidosis of islet cells. Decreased signal on T1-weighted images without inflammation findings on CT and MRI were clues for the diagnosis.

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“…MRI of amyloid deposits which were clearly identifiable in bone have also been shown to have decreased signal intensity on Tl-weighted [6,8] and mildly T2-weighted [6] images. Other reports of abdominal viscera involved with amyloid describe variably altered T1 and T2 relaxation times [1,9,11]. However, calculation of relaxation times in abdominal viscera is often difficult and so the significance of these findings is unclear.…”

Section: Discussionmentioning

confidence: 93%

MRI evaluation of amyloid myopathy

et al. 1992

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Amyloid myopathy is a rare complication of primary amyloidosis. The magnetic resonance imaging (MRI) features of two patients with amyloid myopathy were studied. Slight prolongation of muscle T1 and T2 relaxation times was evident but the striking abnormality was marked reticulation of the subcutaneous fat. The clinical findings of indurated extremities far exceeds the minimal signal intensity alteration seen in the muscles. The MR appearance of amyloid myopathy differs from that of other neuromuscular conditions in the minimal changes found in muscle, but the striking abnormality seen in subcutaneous fat makes it distinct from many neuromuscular conditions.

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MRI of primary amyloidosis

Cited by 30 publications

References 7 publications

Pancreatic involvement in primary amyloidosis: radiologic findings

Pancreatic involvement in primary amyloidosis: radiologic findings

Pancreatic Islet Cell Amyloidosis Manifesting as a Large Pancreas

MRI evaluation of amyloid myopathy

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