MRI of Rectal Cancer: An Overview and Update on Recent Advances

Jhaveri, Kartik; Hosseini-Nik, Hooman

doi:10.2214/ajr.14.14201

Cited by 141 publications

(110 citation statements)

References 89 publications

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“…2D sagittal and coronal T2W Turbo spin echo (TSE) sequences were obtained using the following parameters: repetition time (TR), 3761 ms; echo time (TE), 110 ms; field of view (FOV), 24 × 24 cm; slice thickness, 3 mm with a 0.3-mm gap; acquisition matrix, 336 × 252; NSA, 1. 2D axial T2W TSE sequences were obtained perpendicular to the tumoral axis in the sagittal view [10–11] : TR, 3865 ms; TE, 100 ms; FOV, 14 × 14 cm; slice thickness, 3 mm with a 0.3-mm gap; acquisition matrix, 232 × 228.…”

Section: Methodsmentioning

confidence: 99%

Rectal cancer

Sun

Xu²,

Xu³

et al. 2017

Medicine

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The aim of this study was to evaluate the short-term test-retest reproducibility of diffusion-weighted magnetic resonance imaging (DW-MRI) parameters of rectal cancer with 3.0T MRI.Twenty-six patients with rectal cancer underwent MRI, including diffusion-weighted imaging with 8 b values. Apparent diffusion coefficient (ADC) and intravoxel incoherent motion (IVIM) parameters (D, pure diffusion; f, perfusion fraction; D∗, pseudodiffusion coefficient) were, respectively, calculated. The short-term test-retest reproducibility, the intra and interobserver variation of the IVIM parameters were assessed based on the repeatability coefficient and Bland-Altman limits of agreement.There was no significant intra or interobserver difference observed in the parameters on the same DW-MRI scan. The corresponding repeatability coefficient of intra- and interobserver analysis for ADC, D, f, and D∗ was 5.4%, 11.1%, 55.4%, and 40.3%; 10.9%, 41.6%, 134.0%, and 177.6%, respectively. The test-retest repeatability coefficient for ADC, D, f, and D∗ was 19.1%, 24.5%, 126.3%, and 197.4%, respectively, greater than the intraobserver values.ADC and D have better short-term test-retest reproducibility than f and D∗. Considering the poor test-retest reproducibility for f and D,∗ variance in these 2 parameters should be interpreted with caution in longitudinal studies on rectal cancer in which treatment response and recurrence are monitored.

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Section: Methodsmentioning

confidence: 99%

Rectal cancer

Sun

Xu²,

Xu³

et al. 2017

Medicine

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“…MRI has not met expectations in re-staging, especially in complete response evaluation after neoadjuvant CRT because of post-therapeutic fibrosis and inflammation[15-19]. However, adding functional MR sequences such as dynamic contrast-enhanced and diffusion-weighted sequences to the standard approach can improve diagnostic accuracy of MRI[20-23].…”

Section: Introductionmentioning

confidence: 99%

Magnetic resonance imaging for diagnosis and neoadjuvant treatment evaluation in locally advanced rectal cancer: A pictorial review

Engin

Sharifov

2017

WJCO

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High-resolution pelvic magnetic resonance imaging (MRI) is the primary method for staging rectal cancer. MRI is highly accurate in the primary staging of rectal cancer; however, it has not proven to be effective in re-staging, especially in complete response evaluation after neoadjuvant therapy. Neoadjuvant chemoradiotherapy produces many changes in rectal tumors and on adjacent area, as a result, local tumor extent may not be accurately determined. However, adding diffusion-weighted sequences to the standard approach can improve diagnostic accuracy. In this pictorial review, an overview of the situation of MRI in the staging and re-staging of rectal cancer is exhibited as a pictorial assay. An experience- and literature-based discussion of limitations and difficulties in interpretation are also presented.

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“…We also do a delayed post-contrast sequence in a perpendicular plane to the dynamic series. While the addition of contrast-enhanced sequences has not been shown to add accuracy for assessment of T stage [13], in our institution we have found these sequences to be beneficial for detection of small tumors, characterization of lymph nodes, assessing treatment response, and evaluation of incidental pelvic or bone abnormalities [14,15]. Diffusion weighted imaging (DWI) is included in the protocol at our institution to facilitate assessment of post chemoradiation treatment response as an adjunct to T2 and contrast-enhanced T1 imaging [16].…”

Section: Mri Protocolmentioning

confidence: 71%