MRI of the lung – state of the art

Wielpütz, Mark O.; Kauczor, Hans‐Ulrich

doi:10.4261/1305-3825.dir.5365-11.0

Cited by 118 publications

(144 citation statements)

References 48 publications

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“…81 In addition to the use of inhaled gases, there may be a role for conventional (proton) MRI in evaluation of emphysema. [82][83][84][85] Advances in MRI imaging of the lung can result in visualization of low-proton areas of emphysema in at least 50% of cases. …”

Section: Mrimentioning

confidence: 99%

Progress in Imaging COPD, 2004 - 2014

Lynch¹

2014

J COPD F

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Abbreviations: computed tomography, CT; magnetic resonance imaging, MRI; positron emission tomography, PET; Global Initiative for chronic Obstructive Lung Disease, GOLD; quantitative CT, QCT; Hounsfield Units, HU; percentage of low attenuation area, %LAA; relative area of lung less than -950 HU, RA950; Evaluation of COPD Longitudinally to Identify Predictive Surrogate Endpoints, ECLIPSE; forced expiratory volume in 1 second, FEV1; forced vital capacity, FVC. Journal of the COPD Foundation(GOLD) stage may have substantial, little, or no emphysema. Discrete subphenotypes of COPD include emphysema of varying morphologic appearance, large airway abnormality and small airway obstruction. Increasing awareness of the heterogeneity of COPD has led to increased use of CT to characterize COPD for purposes of genetic evaluation and identification of specific subgroups which may be amenable to therapeutic trials. 1-3 While visual assessment is important in determining the presence and character of emphysema, the last decade has been characterized by increasing use of quantitative imaging to provide precise estimates of the severity and distribution of emphysema, gas trapping and airway wall thickening. Several large cohorts of cigarette smokers have now been quite extensively characterized by CT, resulting in increased knowledge of the clinical correlates of quantitative CT parameters. [4][5][6] The purpose of this paper is to present the substantial contribution that imaging has made to our understanding of COPD over the past 10 years. AbstractComputed tomography (CT) has contributed substantially to our understanding of COPD over the past decade. Visual and quantitative assessments of CT in COPD are complementary. Visual assessment should provide assessment of centrilobular, panlobular and paraseptal emphysema, airway wall thickening, bronchiectasis, findings of respiratory bronchiolitis, and enlargement of the pulmonary artery. Quantitative CT permits evaluation of severity of emphysema, airway wall thickening, and expiratory air trapping, and is now being used for longitudinal evaluation of the progression of COPD. Innovative techniques are being developed to use CT to characterize the pattern of emphysema and smoking-related respiratory bronchiolitis. Magnetic resonance imaging (MRI) and positron emission tomography PET-CT are useful research tools in the evaluation of COPD.

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Section: Mrimentioning

confidence: 99%

Progress in Imaging COPD, 2004 - 2014

Lynch¹

2014

J COPD F

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“…scans show small but unavoidable, involuntarily different breath-hold positions even at end-expiration, as outlined in Figures 4a and 4b 2 ), even marginal lung volume differences will lead to signal modulations of comparable strength. This generally leads to a large variability and thus imprecise determination of the oxygen enhancement from only two datasets, as exemplarily demonstrated in Figure 4c.…”

Section: Signal Intensity Variability At Functional Residual Capacitymentioning

confidence: 93%

“…In Equation [2], h refers to the SI in the limit of infinite volume, i.e. noise, and a (%1) maps the lung expansion and changes in pulmonary blood volume during breathing.…”

Section: Respiratory-related Signal Modulation In Balanced Ssfp: the mentioning

confidence: 99%

Three‐dimensional oxygen‐enhanced MRI of the human lung at 1.5T with ultra‐fast balanced steady‐state free precession

Pusterla

Bauman

Bieri

2017

Magnetic Resonance in Med

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Purpose: To assess the feasibility of 3D oxygen-enhanced (OE) MRI of the lung at 1.5T using multi-volumetric ultra-fast balanced steady-state free precession (ufSSFP) acquisitions. Methods: Isotropic imaging of the lung for OE-MRI was performed with an adapted 3D ufSSFP sequence using five breathhold acquisitions ranging from functional residual capacity to tidal inspiration under both normoxic (room air) and hyperoxic (100% O 2 ) gas conditions. For each O 2 concentration, a sponge model (which captures the parenchymal signal intensity variation as a function of the lung volume) was fitted to the acquired multivolumetric datasets after semiautomatic lung segmentation and deformable image registration. From the retrieved model parameters, 3D oxygen-enhancement maps were calculated. Results: For OE ufSSFP imaging, the maximum parenchymal signal is observed for flip angles around 23 under both normoxic and hyperoxic conditions. It is found that the sponge model accurately describes parenchymal signal at different breathing positions, thereby mitigating the confounding bias in the estimated oxygen enhancement from residual density modulations. From the model, an average lung oxygen enhancement of 7.0% 6 0.3% was found in the healthy volunteers, and the oxygenenhancement maps indicate a ventral to dorsal gravitation-related gradient. Conclusion:The study demonstrates the feasibility of wholelung OE-MRI from multi-volumetric ufSSFP in healthy volunteers.

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“…26 İyonize radyasyon kullanılmamaktadır. 27 Bazı üst limitlere uyulduğu takdirde hiçbir biyolojik zararı bulunmamaktadır. 28 Çocuklarda ve hamilelerde kullanılabilmek-tedir.…”

Section: Manyeti̇k Rezonans Görüntülemeni̇n Avantajlariunclassified

Should Brackets be Removed Before Magnetic Resonance Imaging?

Camcı¹

2018

Turkiye Klinikleri J Dental Sci

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Ö ÖZ ZE ET T Manyetik rezonans görüntüleme sistemi (MRG), 20 yılı aşkın süredir tıpta ve diş hekimliğinde kullanılan, iyonize radyasyon içermeyen, noninvaziv bir görüntüleme sistemidir. MRG yumuşak doku kontrastı en yüksek görüntüleme sistemidir ve migren, epilepsi, serebral palsi, menisküs, beyin tümörleri gibi birçok hastalığın teşhisinde yaygın olarak kullanılmaktadır. Ancak; MRG çekiminde, metal varlığı görüntüde artefakta yol açmaktadır. Artefakt ise teşhisi zorlaştır-makta veya imkansızlaştırmaktadır. Artefaktın boyutu; metalin manyetik duyarlılığına (ferromanyetik, diyamanyetik, paramanyetik), şekline, boyutuna, açısına, homojenitesine, MRG cihazının manyetik alan gücüne (low-field, high-field, ultra-high field) ve görüntüleme protokolüne göre değişkenlik göstermektedir. Son yıllarda özellikle baş-boyun bölgesinden alınacak MRG öncesi sık-lıkla ortodontistlerden sabit ortodontik aygıtları çıkarması istenir; ancak "debonding" işlemi, mineye zarar verme potansiyelinin dışında vakit kaybına yol açan maliyetli bir süreçtir. Ortodontide kullanılan malzemeler çok çeşitli alaşımlardan (paslanmaz çelik, titanyum, krom-kobalt, seramik) yapılmaktadır ve her birinin manyetik duyarlılığı ve artefakta yol açma potansiyeli birbirinden farklıdır. Ayrıca; sabit ortodontik aygıtlar MRG' de görüntülenmek istenen anatomik alanın uzaklığına bağlı olarak ilgili bölgede değişen oranlarda artefakta yol açabilir ya da açmayabilir. Bu ça-lışmada; MRG nedir?, MRG'nin avantajları ve dezavantajları, manyetik alan kuvvetinin ortodontide kullanılan materyaller üzerine etkileri, Ortodontik aygıtların MRG üzerine etkileri gibi konu baş-lıkları altında MRG öncesi braketlerin çıkarılıp çıkarılmamasına karar vermede ortodontistlere yardımcı olacak bilgilerin sunulması amaçlanmıştır.A An na ah ht ta ar r K Ke el li im me el le er r: : Manyetik rezonans görüntüleme; artefaktlar (insan eliyle yapılmış); ortodontik gereçler; ortodontik braketler A AB BS ST TR RA AC CT T Magnetic resonance imaging system (MRI) is used in medicine and dentistry for more than 20 years, it does not include ionizing radiation which is a noninvasive imaging system. MRI enables highest contrast visualization of soft tissue and is widely used in the diagnosis of many diseases such as migraine, epilepsy, cerebral palsy, meniscus, brain tumors. But; the presence of metal in MRI leads to artifacts and artifact makes diagnosis difficult or impossible. The size of the artifact depends on the magnetic susceptibility of the metal (ferromagnetic, diamagnetic, paramagnetic), shape, size, angle, homogeneity, magnetic field power (low-field, highfield and ultra-high field) and imaging protocol of the MRI device. In recent years, it is often asked to remove fixed orthodontic devices from orthodontists, especially before the MRI taken from the head and neck region; but the debonding procedures is a costly process that leads to a loss of time other than the potential for damaging the enamel. Materials used in orthodontics are made from a wide variety of alloys (stainless steel, tit...

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MRI of the lung – state of the art

Cited by 118 publications

References 48 publications

Progress in Imaging COPD, 2004 - 2014

Progress in Imaging COPD, 2004 - 2014

Three‐dimensional oxygen‐enhanced MRI of the human lung at 1.5T with ultra‐fast balanced steady‐state free precession

Should Brackets be Removed Before Magnetic Resonance Imaging?

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