MRI reveals structural abnormalities in patients with idiopathic generalized epilepsy

Abstract

Twenty-four percent of patients with idiopathic generalized epilepsies had MRI abnormalities. However, the majority of these abnormalities were nonspecific.

MRI findings in people with epilepsy and nodding syndrome in an area endemic for onchocerciasis: An observational study

“…Changes in the hippocampus were seen in over 20% of PWE, which may cause complex partial seizures, including head nodding in children. 32 Interestingly, all but one PWE with hippocampus changes in our study had seizures in the context of either focal epilepsy or NS. In our study, no significant relationship between febrile convulsions and hippocampus changes was found.…”

“…However, hippocampus changes were not more frequent than in PWE with focal seizures and therefore may be an accidental finding without implication for seizure generation in children/adolescents with NS or, alternatively, some of the children/adolescents with NS may indeed suffer from complex partial epilepsy which clinically appears as head nodding. 32 Limitations of the study This is more of a descriptive study of MRI pathologies in PWE and children/adolescents with NS from an O. volvulus endemic area. In this context statistical analysis of MRI pathologies and their relationship with onchocerciasis must be interpreted with care due to the small sample size.…”

Utility of Magnetic Resonance Imaging (MRI) and It’s Comparison with Electroencephalogram (EEG) in First Onset Seizures in Children

“…If, however, the MRI shows a structural lesion that is the likely source of the seizures, then they can be classified as partial. 16 Among the nonepileptogenic abnormalities detected on MRI, non-specific white matter hyper intensities was the most frequent finding followed by mild cerebral atrophy. Hence these subjects were not included under the MRI positive group.…”

Seizure Semiology: An Overview of the ‘Inverse Problem’

“…Visual auras are also described, and they tend to occur as very brief flashing sensations [75]. All these falsely localizing signs might reflect the occurrence of – mostly nonspecific – structural brain abnormalities, which have been described in up to 1 in 4 patients with IGE and, again, seem to correlate with the degree of EEG focal features [76], a not uncommon occurrence in this diagnostic group [72,77]. …”