2024
DOI: 10.18699/vjgb-24-39
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mRNA-lncRNA gene expression signature in HPV-associated neoplasia and cervical cancer

E. D. Kulaeva,
E. S. Muzlaeva,
E. V. Mashkina

Abstract: Cervical cancer is one of the most frequent cancers in women and is associated with human papillomavirus (HPV) in 70 % of cases. Cervical cancer occurs because of progression of low-differentiated cervical intraepithelial neoplasia through grade 2 and 3 lesions. Along with the protein-coding genes, long noncoding RNAs (lncRNAs) play an important role in the development of malignant cell transformation. Although human papillomavirus is widespread, there is currently no well-characterized transcriptomic signatur… Show more

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