2015
DOI: 10.1002/jemt.22479
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MRT letter: A unified accelerated maximum likelihood technique for widefield, confocal, and super‐resolution 4Pi microscopy

Abstract: We propose an algorithmic technique for accelerating maximum likelihood (ML) algorithm for image reconstruction in fluorescence microscopy. This is made possible by integrating Biggs-Andrews (BA) method with ML approach. The results on widefield, confocal, and super-resolution 4Pi microscopy reveal substantial improvement in the speed of 3D image reconstruction (the number of iterations has reduced by approximately one-half). Moreover, the quality of reconstruction obtained using accelerated ML closely resembl… Show more

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