MS Detectors

Koppenaal, David W.; Barinaga, Charles J.; Denton, M. Bonner; Sperline, Roger P.; Hieftje, Gary M.; Schilling, Gerhard; Andrade, Francisco J.; Barnes, James H.; IV, IV

doi:10.1021/ac053495p

Cited by 85 publications

(62 citation statements)

References 31 publications

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“…However, only few reports investigate alternative detection options. In a recent review by Koppenaal et al [78] the limitations of presently available mass detectors are described and new developments are discussed. From these, the focal-plane array detector seems very promising.…”

Section: New Mass Spectrometry Optionsmentioning

confidence: 99%

Methods using stable isotopes to measure nitric oxide (NO) synthesis in the l-arginine/NO pathway in health and disease

Eijk

Luiking

Deutz

2007

Journal of Chromatography B

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Section: New Mass Spectrometry Optionsmentioning

confidence: 99%

Methods using stable isotopes to measure nitric oxide (NO) synthesis in the l-arginine/NO pathway in health and disease

Eijk

Luiking

Deutz

2007

Journal of Chromatography B

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“…Some specifications for an ideal MS detector are listed in Koppenaal et al [39] Among them there is no charge-state derivation because it is essentially impossible by using conventional MS instruments. All parts of conventional MS instruments have no ability to measure charge states (ze).…”

Section: Charge Discrimination and True Mass Spectrometrymentioning

confidence: 99%

Superconducting nano-strip particle detectors

Cristiano

Ejrnæs

Casaburi

et al. 2015

Supercond. Sci. Technol.

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We review progress in the development and applications of superconducting nano-strip particle detectors. Particle detectors based on superconducting nano-strips stem from the parent devices developed for single-photon detection (SSPD) and share with them ultrafast response time (sub-nanosecond) and operation at a relatively high temperature (2 -5 K) with respect to other cryogenic detectors. SSPDs have been used in the detection of electrons, neutral and charged ions, and biological macromolecules. Nevertheless, the development of superconducting nano-strip particle detectors has been mainly driven by the use in time-of-flight mass spectrometers (TOF-MS) where the goal of 100% efficiency at large mass values can be obtained. A special emphasis will be given to this case, reporting the great progress achieved which permits to overcome the limitations of existing mass spectrometers represented by low detection efficiency at large masses and charge/mass ambiguity and could represent a breakthrough in the field. In this review article we will introduce the device concept and detection principle, stressing the peculiarities of the nano-strip particle detector as well as its similarities with the photon detector. The development of the parallel strip configuration is introduced and extensively discussed, since it has contributed to significant progress in TOF-MS applications.

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“…Other inductive detectors have also been used (Park et al, 1994). Sensitivity, accuracy, and response time are importantparameters that distinguish different ion detection system (Koppenaal et al, 2005). High accuracy and fast-response times usually are mutually exclusive features, therefore, the fast-response electron multiplier required to follow rapid scans (e.g.…”

Section: Detectorsmentioning

confidence: 99%

Principles and Applications of LC-MS/MS for the Quantitative Bioanalysis of Analytes in Various Biological Samples

Kang¹

2012

Tandem Mass Spectrometry - Applications and Principles

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MS Detectors

Cited by 85 publications

References 31 publications

Methods using stable isotopes to measure nitric oxide (NO) synthesis in the l-arginine/NO pathway in health and disease

Methods using stable isotopes to measure nitric oxide (NO) synthesis in the l-arginine/NO pathway in health and disease

Superconducting nano-strip particle detectors

Principles and Applications of LC-MS/MS for the Quantitative Bioanalysis of Analytes in Various Biological Samples

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