2023
DOI: 10.1128/msphere.00271-23
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mSphere of Influence: Systemic decoding gene function in Toxoplasma gondii pathogenesis—CRISPR screens and beyond

Abstract: Yifan Wang works in the field of molecular parasitology with a focus on host-pathogen interactions. In this mSphere of Influence article, he reflects on how papers entitled “A genome-wide CRISPR screen in Toxoplasma identifies essential apicomplexan genes” by S. M. Sidik, D. Huet, S. M. Ganesan, M.-H. Huynh, et al. (Cell 166:1423.e12–1435.e12, 2016, https://doi.org/10.1016/j.cell.2016.08.019 ) and “Mapping host-microbe transcriptional interactions by dual Perturb… Show more

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