MTA versus Ca(OH)2 in apexification of non-vital immature permanent teeth: a randomized clinical trial comparison

Bonte, Éric; Beslot, Aurélie; Boukpessi, Tchilalo; Lasfargues, Jean‐Jacques

doi:10.1007/s00784-014-1348-5

Cited by 75 publications

(88 citation statements)

References 24 publications

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“…ability, and their setting is not greatly affected by moisture (Camilleri 2015, Prati & Gandolfi 2015. The use of MTA for various endodontic applications such as direct pulp capping (Okiji & Yoshiba 2009, Li et al 2015, root-end filling (C ßalıs ßkan et al 2016), perforation repair (Krupp et al 2013) and apical barrier formation in teeth with open apexes (Bonte et al 2015) is reported to result in promising clinical outcomes.…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

et al. 2017

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Yamamoto S, Han L, Noiri Y, Okiji T. Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement. International Endodontic Journal, 50, e73-e82, 2017. Aim To evaluate the Ca 2+ -releasing, alkalizing and apatite-like surface precipitate-forming abilities of a prototype tricalcium silicate cement, which was mainly composed of synthetically prepared tricalcium silicate and zirconium oxide radiopacifier. Methodology The prototype tricalcium silicate cement, white ProRoot MTA (WMTA) and TheraCal LC (a light-cured resin-modified calcium silicate-filled material) were examined. The chemical compositions were analysed with a wavelength-dispersive X-ray spectroscopy electron probe microanalyser with an image observation function (SEM-EPMA). The pH and Ca 2+ concentrations of water in which the set materials had been immersed were measured, and the latter was assessed with the EDTA titration method. The surface precipitates formed on the materials immersed in phosphate-buffered saline (PBS) were analysed with SEM-EPMA and X-ray diffraction (XRD). Kruskal-Wallis tests followed by Mann-Whitney U-test with Bonferroni correction were used for statistical analysis (a = 0.05).Results The prototype cement contained Ca, Si and Zr as major elemental constituents, whereas it did not contain some metal elements that were detected in the other materials. The Ca 2+ concentrations and pH of the immersion water samples exhibited the following order: WMTA = prototype cement > TheraCal LC (P < 0.05). All three materials produced Ca-and P-containing surface precipitates after PBS immersion, and the precipitates produced by TheraCal LC displayed lower Ca/P ratios than those formed by the other materials. XRD peaks corresponding to hydroxyapatite were detected in the precipitates produced by the prototype cement and WMTA. Conclusion The prototype tricalcium silicate cement exhibited similar Ca 2+ -releasing, alkalizing and apatite-like precipitate-forming abilities to WMTA. The Ca 2+-releasing, alkalizing and apatite-like precipitate-forming abilities of TheraCal LC were lower than those of the other materials.

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Section: Introductionmentioning

confidence: 99%

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

et al. 2017

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“…, Bonte et al . ). In the present prospective randomized comparative clinical study, in addition to strict patient enrolment criteria, a standardized clinical treatment protocol was established as follows: care was taken not to overextend the instrumentation, disinfection of the root canal was provided with NaOCI, EDTA and finally CHX, CH paste was kept in contact with the periapical tissues and changed until occurrence of apical barrier formation for CH group, whilst CH paste was used in the MTA group for a week.…”

Section: Discussionmentioning

confidence: 97%

“…, Bonte et al . ), a physical apical barrier was not used and MTA was placed gently step by step with radiographic examination, and the location of the MTA was checked immediately after placement. In the present study, a similar protocol was utilized and careful radiographic examination was performed during the placement of the MTA in order to prevent its extrusion.…”

Section: Discussionmentioning

confidence: 99%

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Treatment of immature teeth with nonvital pulps in adults: a prospective comparative clinical study comparingMTAwith Ca(OH)₂

et al. 2019

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Aim To evaluate and compare the influence of various predictors on outcomes of apexification using either mineral trioxide aggregate (MTA) or calcium hydroxide (CH) in permanent immature anterior teeth with necrotic pulps and periapical lesions of adults. Methodology Ninety immature teeth with necrotic pulps and periapical lesions on adult patients (aged 18–40 years) were treated with MTA (45 teeth) or CH (45 teeth) between 2015 and 2018. Patients of both groups were recalled for follow‐up examinations after the first intervention at 1,3,6 and 12 months for the first year, every 6 months for the second year and every year thereafter until the end of the study (median 32.3 months). The treatment outcome based on clinical and radiographic criteria was assessed by calibrated examiners and dichotomized as ‘healed+healing’ or ‘not healed’. The age, gender, stage of root development, preoperative signs and symptoms of apical periodontitis and size of periapical lesion were recorded. The cumulative success proportion and mean time were analysed with the Kaplan–Meier test. The generalized logrank statistic was used to describe prognostic clinical variables. Fisher's exact test was applied for the evaluation of the healing rates. Results Thirty‐nine of the 45 teeth treated with MTA were available for recall. Of these, 29 teeth (74%) revealed calcific apical barrier formation with complete resolution of periapical lesions, 7 teeth (18%) were healing, and 3 teeth (8%) had persistent disease. Thirty‐four of the 45 teeth in the CH group were available for recall. Of these, 27 teeth (79%) had complete healing of periapical lesions and had calcific barrier formation, 4 teeth (12%) were healing, and the remaining 3 teeth (9%) had not healed. The survival rate of teeth treated with MTA was similar to the survival rates observed in teeth treated with CH (90% and 91%, respectively, P > 0.05). The generalized logrank statistic revealed that the cumulative success rate of both materials was not significantly different (P > 0.05). None of the tested predictors had an influence on the treatment outcomes of teeth in both groups (P > 0.05). Conclusions Apexification with both MTA and CH was associated with similar treatment outcomes. MTA may be proposed as a material for apexification treatment in immature teeth of adult patients due to the shorter treatment time associated with its use.

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“…Therefore, MTA yields favorable results when used as retrofilling material, allowing the formation of mineralized tissue 32,33 and presenting no inflammation. For instance, MTA can be used in the pulpectomy of both deciduous and permanent teeth or as an apical barrier in teeth with pulp necrosis and open apices, with or without previous treatment with sodium hydroxide.…”

Section: Discussionmentioning

confidence: 99%

Endodontic reintervention with MTA apical plug: a case report

Virgens¹,

Silva²,

Pereira³

et al. 2015

Dental Press Endod

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Introduction: Chemical-mechanical preparation is of crucial importance to a successful endodontic treatment. Endodontic reintervention is indicated in cases of failure and unsuccessful outcomes. In this phase, teeth with external apical resorption require excellent care by the practitioner. In order to overcome these challenges, a biomaterial known as MTA (Mineral Trioxide Aggregate) was incorporated to the world dental market, presenting several indications, such as its use as apical plug. Objective: To report a clinical case of endodontic reintervention with indication of MTA apical plug. Case report: A Caucasian female patient reported sensitivity to palpation and presence of fistula for more than 15 days. Gingivitis and fistula were clinically observed at the bottom of the buccal sac of tooth #21. Radiographically, previous endodontic treatment was poor, presenting intraradicular metal core, external root resorption, and rarefying osteitis limited to the periapical region. Endodontic reintervention of tooth #21 was carried out. Treatment involved three visits for removal of the temporary crown, cast metal core and gutta-percha, in addition to application of intracanal dressing and the use of a MTA apical plug, as well as the application of warm gutta-percha. Thereafter, the patient was referred for definitive rehabilitating treatment. Conclusion: Clinical and radiographic follow-up after eight years revealed periapical repair and re-establishment of masticatory and esthetical functions by means of restorative procedure. Treatment was proven to be efficient in sealing the apical region of the root canal through the use of MTA apical plug; thus, showing the success and advantages of both material and therapeutic modality.

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MTA versus Ca(OH)2 in apexification of non-vital immature permanent teeth: a randomized clinical trial comparison

Abstract: Apexification using MTA seems preferable to CH in order to early achieve the coronoradicular filling and to limit the risk of root fracture.

Cited by 75 publications

References 24 publications

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

Treatment of immature teeth with nonvital pulps in adults: a prospective comparative clinical study comparingMTAwith Ca(OH)₂

Endodontic reintervention with MTA apical plug: a case report

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MTA versus Ca(OH)2 in apexification of non-vital immature permanent teeth: a randomized clinical trial comparison

Abstract: Apexification using MTA seems preferable to CH in order to early achieve the coronoradicular filling and to limit the risk of root fracture.

Cited by 75 publications

References 24 publications

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

Evaluation of the Ca ion release, pH and surface apatite formation of a prototype tricalcium silicate cement

Treatment of immature teeth with nonvital pulps in adults: a prospective comparative clinical study comparingMTAwith Ca(OH)2

Endodontic reintervention with MTA apical plug: a case report

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Treatment of immature teeth with nonvital pulps in adults: a prospective comparative clinical study comparingMTAwith Ca(OH)₂