MTX Could Be First-Line Therapy Even in Cases Where hCG Level is Greater than 5,000 IU/ml

Predictors of Success of Medical Management of Ectopic Pregnancy in a Tertiary Care Hospital in United Arab Emirates

“…However exact increase in such risk was not given by Stika et al, They found a success rate of 84.6% with repeated injections of MTX. In another study by Yoshika Yamashita et al, [16] done on 44 Japanese women it was concluded that a serum Beta HCG level > 5,000 mIU/ml is not necessarily resistant to MTX treatment, and patients with interstitial pregnancy are particularly good candidates for conservative treatment even if initial HCG is > 5,000 IU/ml. However the number of cases with initial Beta HCG >5,000 mIU/ml who were treated with MTX in this study was only 14.…”