Mucinosis eritematosa reticular

Serrano, Antonio Garrido; Rodríguez, Lourdes; Conejo‐Mir, Julián

doi:10.1016/s0001-7310(04)76826-x

Cited by 7 publications

(6 citation statements)

References 12 publications

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“…Certain disorders, especially autoimmune diseases such as systemic LE, diabetes mellitus, and idiopathic thrombocytopenic purpura, have been associated 5 . The condition has a certain degree of overlap with LE, as they share a series of common elements including: clinical manifestations, exacerbation after exposure to sunlight, mucin deposits, granular IgM deposits along the dermal–epidermal junction, and response to antimalarial drugs 13–16 . REM has been strongly associated with a subset of chronic cutaneous LE called tumid lupus.…”

Section: Clinical Featuresmentioning

confidence: 99%

“…5 The condition has a certain degree of overlap with LE, as they share a series of common elements including: clinical manifestations, exacerbation after exposure to sunlight, mucin deposits, granular IgM deposits along the dermal-epidermal junction, and response to antimalarial drugs. [13][14][15][16] REM has been strongly associated with a subset of chronic cutaneous LE called tumid lupus. Tumid lupus usually presents with erythematous, non-scarring, urticaria-like plaques with no associated surface changes.…”

Section: Clinical Featuresmentioning

confidence: 99%

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Reticular erythematous mucinosis – a review

et al. 2012

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Reticular erythematous mucinosis (REM) is a rare cutaneous condition often referred to as plaque-like mucinosis and midline mucinosis. Although the exact etiology remains undefined, efforts to elucidate pathogenesis, disease associations, and prospective treatment modalities have been encouraging. Induction of the disease has been associated with viral processes, solar irradiation, specific cell lines, and cytokines such as Interleukin (IL)-1β. Clinically, patients typically develop erythematous macules and papules that coalesce into reticulated patterns on the midline of the chest or back. The lesions have a tendency to respond to systemic antimalarial therapy, but novel therapeutic approaches with ultraviolet A1 light (UVA1) and pulse dye laser (PDL) have been promising. Histologically, REM is associated with a mild, predominantly lymphocytic infiltrate with variable deep perivascular extension. Mucin may be seen in the upper and mid dermis and is prominent around the infiltrate and appendages. IgM deposits may be visualized under direct immunoflourescence along the basal layer. Because of the similarities between REM and tumid lupus, the two disease processes have often been grouped together. The remarkable overlap between the two diseases suggests that the two conditions may actually be the same disease.

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Section: Clinical Featuresmentioning

confidence: 99%

Section: Clinical Featuresmentioning

confidence: 99%

Reticular erythematous mucinosis – a review

et al. 2012

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“…Desde el punto de vista clínico, la MER se caracteriza por la aparición de máculas o placas eritematosas e infiltradas que, con el tiempo, toman un aspecto reticulopigmentado y, en raras ocasiones, pueden observarse telangiectasias 4,7 . La erupción suele ser asintomática, pero el 30% de los pacientes refieren prurito [5][6] .…”

Section: Comentariosunclassified

“…En algunos casos, se observa una degeneración vacuolar leve de la capa basal 5 . Con la tinción de alcian blue es posible evidenciar el depósito de mucina en la dermis 7,8 . La separación de los haces de colágeno dérmico es un sello distintivo de la MER 4 .…”

Section: Comentariosunclassified

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Mucinosis eritematosa reticular con buena respuesta al tratamiento tópico

et al. 2019

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La mucinosis eritematosa reticular es una forma rara de mucinosis cutánea, de etiología e incidencia desconocidas, que predomina en mujeres de mediana edad. La clínica y la histopatología son fundamentales para arribar al diagnóstico. Si bien el tratamiento de primera línea es la hidroxicloroquina oral, se han publicado buenos resultados con los tratamientos tópicos. Presentamos los casos de 2 pacientes con diagnóstico de mucinosis eritematosa reticular, con buena respuesta al tratamiento tópico con tacrolimús y corticosteroides. Destacamos la seguridad y el fácil manejo que estos representan en una enfermedad poco frecuente.

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