Mucinous adenocarcinoma of the prostate: Histochemical and immunohistochemical studies

Ro, Jae Y.; Grignon, David J.; Ayala, Alberto G.; Fernández, Pedro; Ordóñez, Nelson G.; Wishnow, Kenneth I.

doi:10.1016/s0046-8177(96)90004-0

Cited by 114 publications

(61 citation statements)

References 17 publications

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“…1,[21][22][23] Using these criteria, these tumors have an incidence of approximately 0.2%. [21][22][23] There are no clinical features to distinguish mucinous carcinoma from usual acinar adenocarcinoma. These tumors cause elevated PSA, metastasize in the usual manner and respond to hormonal therapy.…”

Section: Mucinous (Colloid) Carcinomamentioning

confidence: 99%

“…These tumors cause elevated PSA, metastasize in the usual manner and respond to hormonal therapy. [21][22][23][24][25] This variant is considered to be associated with a worse prognosis than usual acinar adenocarcinoma. In a literature review of 60 mucinous carcinomas, Saito and Iwaki 26 found the 3-and 5-year survivals to be 50 and 25%, respectively.…”

Section: Mucinous (Colloid) Carcinomamentioning

confidence: 99%

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Unusual subtypes of prostate cancer

2004

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The vast majority of prostatic tumors developing in adult males are adenocarcinomas. For the most part, variations in histology have not received specific designations and, from a practical approach, have had any specific prognostic implications handled through application of the Gleason grading system. Nonetheless, some of the adenocarcinoma variants have specific clinical features and differential diagnoses. Furthermore, there has been some controversy regarding the appropriate application of the Gleason grading scheme in these tumors. In addition, there are carcinomas that are in fact not adenocarcinomas and that should be kept as distinct entities. In this paper, the histologic variants of adenocarcinoma are reviewed with emphasis on clinicopathologic features and the clinical relevance of these subtypes. Other carcinomas that occur in the prostate gland are also discussed again with a focus on the clinicopathologic characteristics.

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Section: Mucinous (Colloid) Carcinomamentioning

confidence: 99%

Section: Mucinous (Colloid) Carcinomamentioning

confidence: 99%

Unusual subtypes of prostate cancer

2004

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“…For example, studies have shown that ERG gene expression occurs in 50% of mucinous adenocarcinoma. 9,17 Likewise, TMPRSS2: ERG fusion gene was identified in 83% of these prostate cancers. 18,19 Furthermore, MUC 2 immunoexpression was found in the mucinous elements of MACP.…”

Section: Discussionmentioning

confidence: 98%

“…3 In another study of Ro et al 17 12 cases with high-stage mucinous adenocarcinoma were treated with radiation, hormonal therapy or in a combination, bone metastases were also common. 16 In contrast, Osunkoya et al 20 have reported 5-year progression free risk of 97.2% of cases in a group of 47 patients with mucinous prostatic adenocarcinoma.…”

Section: Discussionmentioning

confidence: 98%

Mucinous adenocarcinoma of the prostate: case report and review of the literature

Otsetov¹,

Kalchev²,

Takova³

et al. 2018

ICPJL

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“…Mucinous adenocarcinoma is common in digestive tract cancer, but is one of the rare variants of prostatic carcinoma. Mucinous adenocarcinoma of the prostate constitutes 0.4% of all prostate malignancies, and only about 50 cases have been reported in literature (5). Immunohistochemical studies of prostate mucinous adenocarcinoma were positive for PSA, PAP and CEA, and there is a 77.8% rate of prostate-specific antigen elevation (6).…”

Section: Discussionmentioning

confidence: 99%

Endobronchial Metastasis from Prostate Cancer Mimicking Primary Lung Cancer

et al. 2010

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F i g u r e 1 . CT s c a n o f c h e s t s h o wi n g a 4 . 4 × 2 . 6 c m, p u l mo n a r y h i l a r ma s s ( a r r o w) i n t h e l e f t l o b e a c c o mp a n i e d b y b r o n c h o s t e n o s i s i n t h e l i n g u l a r s e g me n t , mu l t i p l e n o d u l e s ( a r r o ws ) a n d h i l a r a n d me d i a s t i n a l l y mp h a d e n e c t a s i s . AbstractEndobronchial metastasis from prostate cancer is a rare neoplasm which metastasizes to the proximal central or subsegmental bronchus, in a bronchoscopically visible range. We present a 72-year-old man with a left superior lobar bronchus mass, intrapulmonary metastases, and bone metastases, mimicking primary lung bronchogenic carcinoma. Increasing tPSA, decreasing fPSA/tPSA level, and prostatic puncture pathology proved prostate cancer. Pathomorphology and immunohistochemistry of the mucosa specimen with P504S, PSA revealed the diagnosis of pulmonary metastases from prostate cancer. The patient was treated by hormonal treatment and chemotherapy. He was in remission thirteen months after diagnosis.

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Mucinous adenocarcinoma of the prostate: Histochemical and immunohistochemical studies

Cited by 114 publications

References 17 publications

Unusual subtypes of prostate cancer

Unusual subtypes of prostate cancer

Mucinous adenocarcinoma of the prostate: case report and review of the literature

Endobronchial Metastasis from Prostate Cancer Mimicking Primary Lung Cancer

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