Mucinous adenocarcinoma of the renal pelvis with adenocarcinoma in situ of the ureter

Abstract

Primary epithelial tumor of the renal pelvis is rare, and adenocarcinomas account for less than 1% of malignancies arising from the epithelium of the renal pelvis. We describe in this study a case of a 56-year old male patient who presented with an abdominal mass and dull aching pain for one year. A diagnosis of hydronephrosis of the right kidney was made based on imaging studies. Grossly, the entire kidney was converted into a cystic mass measuring 16 × 12 × 10 cm and filled with gelatinous material along with staghorn calculi in the pelvis measuring 7 × 4 × 3 cm. Histological examination of the tumor showed glands, cysts, and papillae lined by pseudostratified columnar epithelium with hyperchromatic nuclei. Scattered signet ring-type cells were also seen floating in large pools of extracellular mucin. Sections from the ureter showed a component of adenocarcinoma in situ. No invasive tumor was identified in ureteric tissue. Thus, a diagnosis of mucinous adenocarcinoma of the renal pelvis with in situ adenocarcinoma of the ureter was made.

Primary enteric-type mucinous adenocarcinoma of the renal pelvis masquerading as cystic renal cell carcinoma: A case report and review of the literature

“…Ho et al suggested that serum CEA should be checked immediately during or after surgery if the gross examination reveals a hint of the diagnosis [10]. CEA and CA19-9 may act as independent markers for prognosis and recurrence of mucinous adenocarcinoma, however, they can be normal in some cases [1]. Although unique imaging features are lacking to differentiate mucinous adenocarcinoma from common renal tumors, there are some red-flag ideas to share.…”

“…Cases of urinary mucinous adenocarcinoma have previously been reported in the kidney, prostate, bladder, and the ureter [1][2][3][4][5]. Mucinous adenocarcinoma of the renal pelvis is both rare and highly lethal.…”

Primary Adenocarcinoma of the Ureter with Elevated Carbohydrate Antigen-19-9: A Case Report and Review of the Literature

“…Raphael et al [11] have proved that preoperative serum CEA and CA-19-9 levels may be helpful for the diagnosis and act as biomarkers for predicting prognosis and recurrence. Xiong et al [12] reported that only about 100 cases had been reported in the English studies, such as PubMed, Elsevier, Embase, Springer and EBSCO.…”

Tumeurs des cavités pyélocalicielles (CPC)

“…En cas d'adénocarcinome, il faut exclure systématiquement une origine métastatique (renseignements cliniques ++) [11].…”