2020
DOI: 10.1177/1066896920945016
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Mucinous Adenomyomatous Pulmonary Hamartoma: Clinicopathologic, Immunohistochemical, and Molecular Features of 6 Cases

Abstract: Pulmonary hamartoma (PH) may show various combinations of mesenchymal tissues with entrapment of respiratory epithelium. An uncommon variant of PH prevalently consisting of smooth muscle with mucinous proliferation has been reported in literature under several definitions as sporadic reports. We collected a series of 6 leiomyomatous PH associated with mucinous growth from consultation files (3 cases) and multicentric revision of archival files among 128 consecutive surgically resected PH. The lesions have a pr… Show more

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Cited by 4 publications
(8 citation statements)
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“…Unlike the one in our patient, these lesions usually appear in men in the sixth to seventh decade of life. 1 Unlike the 6 tumors published by Rossi et al 1 and others described in the literature, 2,3 the glandular component in our patient was not exclusively mucinous, which, although uncommon, has also been reported in the literature, where branching epithelial clefts characteristic of adenofibroma were identified. 4,5 Therefore, we believe that this type of lesion should be included in the same category.…”
Section: Dear Sirsupporting
confidence: 48%
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“…Unlike the one in our patient, these lesions usually appear in men in the sixth to seventh decade of life. 1 Unlike the 6 tumors published by Rossi et al 1 and others described in the literature, 2,3 the glandular component in our patient was not exclusively mucinous, which, although uncommon, has also been reported in the literature, where branching epithelial clefts characteristic of adenofibroma were identified. 4,5 Therefore, we believe that this type of lesion should be included in the same category.…”
Section: Dear Sirsupporting
confidence: 48%
“…We have carefully read the interesting article “Mucinous Adenomyomatous Pulmonary Hamartoma: Clinicopathologic, Immunohistochemical, and Molecular Features of 6 Cases” 1 published in your journal. We recently observed a similar tumor involving a 76-year-old woman with no other remarkable history who was referred to us for an 8-year history of a solitary pulmonary nodule in the left lower lobe, which, in the last radiological check-up, had increased in size from 1.8 to 2.1 cm (Figure 1a).…”
mentioning
confidence: 99%
“…Histologic investigation classically demonstrates normal adipose cells with intervening collagen. The collagen is often in continuity with SM R et al [7] GW Pereira et al [8] A T-E et al [9] R S, et al [10] Chen X, et al [11] PF C, et al [4] M S, et al [12] Zhang M, et al [13] JC M-H, et al [14] Rossi G [15] Li Y, et al [16] YW H, et al [17] S-100 SM R et al [7] GW Pereira et al [8] A T-E et al [9] R S et al [10] Chen X, et al [11] PF C, et al [4] DJ R et al [12] Zhang M et al [13] JC M-H et al [14] Rossi G et al [15] Li Y, et al [16] YW H et al [17] Calretinin SM R et al [7] GW Pereira et al [8] A T-E et al [9] R S et al [10] Chen X, et al [11] PF C, et al [4] DJ R et al [12] Zhang M et al [13] JC M-H et al [14] Rossi G et al [15] Li Y, et al [16] YW H et al [17] CK27…”
Section: Discussionmentioning
confidence: 98%
“…We summarized the comparison of results of the immunohistochemical features of choristoma and hamartoma in Table 1. [4,[6][7][8][9][10][11][12][13][14][15][16][17]…”
Section: Pathological Findingsmentioning
confidence: 99%
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