Mucinous Cystadenoma in the Lung of a Captive-born Moustached Tamarin (Saguinus mystax)

Abstract

Summary A 2-year-old captive-born male moustached tamarin was subjected to necropsy examination after a fatal head trauma. A solitary, circumscribed, subpleural mass (0.6 cm diameter) was found in the right caudal lung lobe. The mass was diagnosed as a mucinous cystadenoma. Histochemical and immunohistochemical tests were performed to further characterize the tumour. Surfactant proteins A, B, C and D were not found in the neoplastic cells, suggesting that the tumour arose from a non-surfactant producing alveolar lining cell. Pulmonary mucinous cystadenomas are uncommon benign tumours in man and have not been reported previously in animals.

Spontaneous pulmonary adenocarcinoma and subcutaneous cavernous hemangiomas arising in a squirrel monkey (Saimiri sciureus)

“…It was subsequently re‐evaluated and classified as non‐neoplastic pulmonary adenomatosis . Other tumors in NWM include bronchial adenomas in a saddle back tamarin ( Saguinus fuscicollis) and a common marmoset ( Callithrix jacchus ); a small‐cell carcinoma in cotton‐top tamarin ( Saguinus oedipus ); a squamous cell carcinoma in a saddle back tamarin ( Saguinus fuscicollis ); a mucinous cystadenoma in a mustached tamarin ( Saguinus mystax ); and a suspected alveolar carcinoma in a howler monkey ( Alouatta caraya ) …”

Spontaneous pulmonary adenocarcinoma in a common marmoset (Callithrix jacchus)

“…Pulmonary neoplasia is a significant cause of death in humans 8 but uncommon in non‐human primates (NHPs) 9‐13 . The close phylogenetic relationship between humans and NHPs often results in analogous pathology and can allow for investigation as to the etiology of some neoplasms 14 .…”

Spontaneous pulmonary adenosquamous carcinoma in a free‐living black capuchin monkey (Sapajus nigritus)

“…Both benign and malignant, primary and metastatic, conditions have been documented . Primary benign neoplasms reported include bronchioloalveolar, alveolar, and papillary adenomas in rhesus macaques ( Macaca mulatta ); bronchiolar papilloma in a cynomolgus macaque ( Macaca fascicularis ); bronchial adenoma in a common marmoset ( Callithrix jacchus ) and a cotton‐top tamarin ( Saguinus oedipus ); and mucinous cystadenoma in a moustached tamarin ( Saguinus mystax ) . Primary malignant lung tumors described include bronchioloalveolar adenocarcinoma in a bonnet macaque ( Macaca radiata ); clear cell carcinoma in a pigtailed macaque ( Macaca nemestrina ); bronchogenic carcinoma in a blue monkey ( Cercopithecus mitis ), a rhesus macaque and a common langur ( Semnopithecus entellus ); squamous cell carcinoma (SCC) and bronchioloalveolar carcinoma in cynomolgous and rhesus macaques; small cell carcinoma in a cotton‐top tamarin; SCC in saddle‐back tamarins ( Saguinus fuscicollis ); and carcinoid in a rhesus macaque .…”