“…Finally, ischemia develops in the appendiceal wall, which weakens the epithelial integrity and increases the organ's risk of bacterial invasion. Although lymphoid hyperplasia and fecaliths are the most common causative factors of luminal obstruction, other less frequent factors have been associated with the condition, including enterobiasis, 1 endometriosis, 1,16,21 tuberculosis, 1 amebiasis, 1 actinomycosis, 1 adenovirus, 4 granulomatous diseases, 1,7,15,19 eosinophilic granuloma, 8 neurogenic appendicopathy, 11,12 foreign body melanosis, 4 neurofibroma, 4 diverticulitis, 1,9,20 and taeniasis, 1,17,21 as well as appendiceal malignancies, such as carcinoid tumor, 1,13,14 gastrointestinal stromal tumor, 1 hyperplastic polyp, 1 tubular adenoma, 1 villous adenoma, 1 mucocele, 10 mucinous cystadenoma, 1 adenocarcinoma, 1 mucinous cystadenocarcinoma, 1 lymphoma, 1 and leukemia. 1 This study was designed to investigate the occurrence and distribution of unusual pathologic findings encountered in appendectomy specimens of patients who had undergone surgery to treat an initial diagnosis of acute appendicitis.…”