Mucocele Rate Following Nasoseptal Flap Skull Base Repair

Abstract

RESULTS: There was a statistically significant difference in the patients' Lund-Kennedy symptom and Lund-Kennedy endoscopic appearance scores after 6 weeks of rhinotopic therapy. The improvement was sustained after stopping treatment, with a mild drop after a longer follow-up. There was also statistically significant difference in CFUs mucosal bacterial count after therapy and in the prevalence and abundance of bacteria by rt-PCR. Nasoendoscopic guided cultures performed one month after the end of rhinotopic therapy showed resolution of MRSA in 9/13 patients (69.2%). No significant clinical adverse effects were experienced. CONCLUSION: Rhinotopic therapy is an effective treatment strategy for refractory chronic rhinosinusitis associated with MRSA.