Mucocutaneous leishmaniasis: report of a case with massive involvement of nasal, pharyngeal and laryngeal mucosa

Lella, Filippo Di; Vincenti, Vincenzo; Zennaro, D.; Afeltra, Antonella; Baldi, Alfonso; Giordano, Davide; Pasanisi, Enrico; Bacciu, Andrea; Bacciu, S; Lella, Giovanni Di

doi:10.1016/j.ijom.2006.02.015

Cited by 24 publications

(26 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In MCL, Leishmania parasites travel from the skin through the lymphatics and/or blood vessels to the mucous membranes of the mouth, nose, throat, and soft palate (219). This results in the destruction of the naso-oropharyngeal membranes, and perforation of the nasal septum can occur (14,173,264,609). Mucocutaneous leishmaniasis can occur concurrently with a cutaneous infection or months to years after cutaneous lesions heal (219).…”

Section: Leishmaniamentioning

confidence: 99%

Importance of Nonenteric Protozoan Infections in Immunocompromised People

et al. 2010

View full text Add to dashboard Cite

SUMMARY There are many neglected nonenteric protozoa able to cause serious morbidity and mortality in humans, particularly in the developing world. Diseases caused by certain protozoa are often more severe in the presence of HIV. While information regarding neglected tropical diseases caused by trypanosomatids and Plasmodium is abundant, these protozoa are often not a first consideration in Western countries where they are not endemic. As such, diagnostics may not be available in these regions. Due to global travel and immigration, this has become an increasing problem. Inversely, in certain parts of the world (particularly sub-Saharan Africa), the HIV problem is so severe that diseases like microsporidiosis and toxoplasmosis are common. In Western countries, due to the availability of highly active antiretroviral therapy (HAART), these diseases are infrequently encountered. While free-living amoebae are rarely encountered in a clinical setting, when infections do occur, they are often fatal. Rapid diagnosis and treatment are essential to the survival of patients infected with these organisms. This paper reviews information on the diagnosis and treatment of nonenteric protozoal diseases in immunocompromised people, with a focus on patients infected with HIV. The nonenteric microsporidia, some trypanosomatids, Toxoplasma spp., Neospora spp., some free-living amoebae, Plasmodium spp., and Babesia spp. are discussed.

show abstract

Section: Leishmaniamentioning

confidence: 99%

Importance of Nonenteric Protozoan Infections in Immunocompromised People

et al. 2010

View full text Add to dashboard Cite

show abstract

“…10 En la literatura, se menciona un caso de afección traqueal sin estenosis asociado a un compromiso nasal y palatino. 13 Nuestro caso es el primero descrito de leishmaniasis mucosa con afección traqueal en un niño de 12 años, sin factores de riesgo ambientales o personales, ni condiciones anergizantes concomitantes. El diagnóstico de la localización laríngea es difícil y puede ser confundida con una neoplasia.…”

Section: Discussionunclassified

“…1,3,13 Puede haber lesiones concomitantes de la mucosa nasal y senos paranasales, típicamente no dolorosas, 12,13 que se asocian a un malestar nasal y rinorrea serosanguinolenta. 13 Los hallazgos endoscópicos de la leishmaniasis laríngea incluyen ulceración transglótica bilateral, edema perilesional, 3 hipertrofia de bandas ventriculares, 1,14 masas exofíticas de apariencia granular, 14 vegetación ulcerada y granulomas en cuerdas vocales. 5,14 En nuestro paciente, se encontró hipertrofia de la epiglotis y edema glótico y ocupación de la vallécula.…”

Section: Discussionunclassified

Leishmaniasis mucosa nasolaringotraqueal en un adolescente

et al. 2014

View full text Add to dashboard Cite

Presentación de casos clínicos RESUMENLa leishmaniasis es un problema creciente de salud pública, que produce un gran impacto social. La leishmaniasis laríngea y sin puerta de entrada evidente es rara, en especial en pacientes inmunocompetentes. Describimos un caso de leishmaniasis laríngea con extensión traqueal y estenosis secundaria en un adolescente previamente sano y sin factores de riesgo ambiental o personal. Palabras clave: leishmaniasis, mucosa, laringe. ABSTRACTLeishmaniasis is a growing public health problem and it produces a great social impact. Laryngeal leishmaniasis without obvious gateway is rare, especially in immunocompetent patients. We report a case of laryngeal leishmaniasis with tracheal involvement and stenosis on a previously healthy teenager without environmental or personal risk factors.

show abstract

“…En Brasil se utiliza el meglumine, y en Perú y Panamá los estudios existentes se realizaron con estibogluconato 33 . Una revisión Cochrane para Latinoamérica evaluó la eficacia según el tipo de agente específico 34 .…”

Section: Figuraunclassified