Mucocutaneous manifestations of helminth infections

Lupi, Omar; Downing, Christopher; Lee, Michael; Pino, Livia Cristina de Melo; Bravo, Francisco; Giglio, Patricia; Sethi, Aisha; Klaus, Sidney N.; Sangüeza, Omar P.; Fuller, Claire; Mendoza, Natalia; Ladizinski, Barry; Woc-Colburn, Laila; Tyring, Stephen K.

doi:10.1016/j.jaad.2014.11.034

Cited by 33 publications

(32 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In the majority of human cases, microfilariae are not found in the bloodstream and immature worms do not reach full maturity. The mode of transmission of Dirofilaria is through a mosquito bite, which carries infectious larvae that penetrate the host's skin . In the case presented here, the patient presumably became infected via mosquito bite to the leg as an accidental host.…”

Section: Discussionmentioning

confidence: 84%

“…The disease is spread throughout warmer climates, which is supported by the much lower reported prevalence in colder climate areas . D. repens in humans is a frequent disease in endemic areas, notably Europe and Russia, however outside of known enzootic areas, the diagnosis is uncommon . D. immitis pulmonary dirofilariasis predominates in North and South America, Australia, and Japan, which reportedly run in parallel with areas of high canine prevalence …”

Section: Discussionmentioning

confidence: 99%

“…Cutaneous manifestations of D. repens present as unifocal or multifocal erythematous and tender nodules on exposed areas of skin (ie, head, eye, neck, trunk and legs) . The parasite is identified in human hosts in the immature larval stage and is thought to degenerate prior to reaching maturity .…”

Section: Discussionmentioning

confidence: 99%

“…The patient in our case presented with an isolated inoculation and did not show systemic signs of infection, and therefore surgical removal of the worm was sufficient treatment. This is the typical clinical scenario; however in rare cases, systemic filaricide treatment is needed in symptomatic patients …”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Subcutaneous dirofilariasis: a masquerade of a palisaded granulomatous dermatitis

2017

View full text Add to dashboard Cite

Dirofilaria species are roundworms responsible for "heartworm" in canines. On occasion, humans are an accidental host, resulting in pulmonary (Dirofilaria immitis) or extrapulmonary (Dirofilaria repens) manifestations. Of the extrapulmonary sites of involvement, subcutaneous involvement is particularly common. We report a case of a 49-year-old female who presented with an erythematous nodule on her shin, which closely resembled necrobiosis lipoidica on histopathologic examination. On closer examination, there were foci of necrosis that harbored segments of the nematode, diagnostic of dirofiliarisis. We present this case to highlight the histopathologic similarities and differences between palisaded necrobiotic conditions and this potentially underrecognized entity.

show abstract

Section: Discussionmentioning

confidence: 84%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Subcutaneous dirofilariasis: a masquerade of a palisaded granulomatous dermatitis

2017

View full text Add to dashboard Cite

show abstract

“…Ancylostoma sp., also known as a hookworm, is a parasite of wild cats and dogs. Infections with this nematode occur mostly in tropical and subtropical climates due to the warm and humid conditions [26,34,35]. The species that affect the oral mucosa are Ancylostoma brasiliensis and Ancylostoma caninum.…”

Section: Trichomonas Tenax Trichomonas Tenax (Oral Trichomonas)mentioning

confidence: 99%

Symptoms of selected parasitic diseases in the oral cavity

Puzio¹,

Sikora²,

Srebrna³

et al. 2021

J Pre Clin Clin Res.

View full text Add to dashboard Cite

Skin-Colored Nodule on the Scalp of a Middle-aged Man

Khullar

Agarwal²,

Chandra³

2020

JAMA Dermatol

View full text Add to dashboard Cite

An otherwise healthy man in his 40s presented with a 3-month history of an asymptomatic nodule on his scalp. There were no systemic complaints, history of arthropod bite, immunosuppression, travel abroad, or contact with animals in the recent past. Physical examination revealed a skin-colored, firm, nontender, freely mobile 2 × 1.5-cm nodule with overlying normal skin on the right occipital region of the scalp (Figure , A). There was no lymphadenopathy. No other cutaneous lesions were present.The nodule was completely excised and sent for histopathologic examination, which revealed a nodule in the dermis with an unremarkable epidermis. Cross-sections of parasites were present, surrounded by a fibrous capsule (Figure , B). The parasite showed an outer cuticle, muscle layer underneath, and gravid uterus filled with microfilariae (Figure , C). The cuticle demonstrated a wavy pattern of longitudinal ridges on its outer surface (Figure , D). The fibrous capsule contained mixed inflammatory infiltrate of lymphocytes, eosinophils, histiocytes, and plasma cells. Findings of slitlamp examination and fundoscopy of the eyes were normal. Findings of routine hematologic and biochemical investigations were normal. No microfilaria was seen in peripheral blood. Findings of chest radiography and abdomen ultrasonography were unremarkable.

show abstract

Mucocutaneous manifestations of helminth infections

Cited by 33 publications

References 41 publications

Subcutaneous dirofilariasis: a masquerade of a palisaded granulomatous dermatitis

Subcutaneous dirofilariasis: a masquerade of a palisaded granulomatous dermatitis

Symptoms of selected parasitic diseases in the oral cavity

Skin-Colored Nodule on the Scalp of a Middle-aged Man

Contact Info

Product

Resources

About