Mucoepidermoid carcinoma

Abstract

Background: Salivary gland tumors are rare and clinically represent a diverse group of neoplasms among which mucoepidermoid carcinoma (MEC) is a relatively common salivary gland tumor with varying potential for aggressive behavior. The purpose of the study was aimed at to analyze the relative frequency and correlate with age, sex, anatomical site and histological grade of MEC and compare the findings with epidemiological data from different geographic locations. Materials and Methods: Twenty-five cases diagnosed with MEC during the period June 1985 to June 2004 (19 years) were retrieved from the Department of Pathology, Government Medical College and Hospital, Ambajogai, and clinical data were recorded and reviewed histopathologically. Results: The relative frequency of MEC was 13.15%. Low-grade MEC (44%) was the most common, followed by intermediate-grade MEC (36%) and high-grade MEC (20%). The mean age for occurrence of MEC was 44.28 ± 13.29 years. MEC was predominant in females (60%) than males (40%). Thus, the overall female-male ratio was 1.5:1. Among minor salivary glands, palate (48%) was the most common site, and among major salivary glands, parotid gland (16%) was the common site. Conclusion: Comparing the present data with previous studies on MEC, one may infer that some demographic characteristics and the predominance vary in different geographic regions. Analysis of the distribution and particular features of MEC in a specific population helps in establishment of appropriate treatment.

Central mucoepidermoid carcinoma of maxilla a case report and review of literature

“…Among minor salivary glands, the palate (48%) was the most common site, and among major salivary glands, the parotid gland (16%) was the common site. 4 There is a systematic review article reporting molecular determinations of Mucoepidermoid carcinoma (MEC) and adenosquamous carcinoma (ASC) conducted in 2022. Adequate evidence for a distinctive molecular profile of either MEC or ASC was not found.…”

Mucoepidermoid carcinoma of the lower lip: A case report and review of literature

“…[ 2 5 ] Variations in the frequency of specific histologic types and the involvement of major and minor salivary glands have been noted in literature from different parts of the world. [ 3 7 8 9 10 11 ]…”