Mucoepidermoid carcinoma ex pleomorphic adenoma: A rare diagnostically challenging entity

Titinchi, Fadi; Sallies, Moegamat; Wu, Hue-Tsi

doi:10.1016/j.oraloncology.2022.106112

Cited by 2 publications

(4 citation statements)

References 5 publications

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“…The patient presented with a recurrent submandibular mass for 4 years after the excision of a pleomorphic adenoma 12 . A few cases were identified in the palate 2 , 13 , 14 , including the hard palate 13 , soft palate 14 , and hard-soft palate junction 2 . In 2015, a rare tumor was discovered in a 26-year-old man’s alveolar ridge and retromolar trigone 15 .…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, there were three reported cases of lacrimal gland involvement 16 – 18 . A majority of the cases showed the presence of a high-grade tumor, indicating the need for a combination of treatment modalities 2 , 3 , 6 – 9 . However, the low-grade tumor was successfully treated by completely removing it as a single method 3 , 11 , as shown in this case study.…”

Section: Discussionmentioning

confidence: 99%

“…In rare entities, mucoepidermoid carcinoma (MEC) occupies most of them 1 . MEC originating from pleomorphic adenoma is exceedingly rare 2 . Tumor grading is divided into high, intermediate, and low grades 2 .…”

Section: Introductionmentioning

confidence: 99%

“…MEC originating from pleomorphic adenoma is exceedingly rare 2 . Tumor grading is divided into high, intermediate, and low grades 2 . For small, low-grade salivary gland cancer, complete surgical resection is the safest oncological treatment 3 .…”

Section: Introductionmentioning

confidence: 99%

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Medium-sized buccal mucosa defect reconstruction with buccal advancement flap in mucoepidermoid carcinoma ex pleomorphic adenoma: a case report

Srivanitchapoom,

Yata

2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Mucoepidermoid carcinoma (MEC) ex pleomorphic adenoma is a rare type of salivary gland cancer. Surgical resection remains the standard therapy for this malignancy. After tumor removal, larger defects may require a local, regional, or free flap, while smaller ones can be closed primarily. Managing medium-sized defects can be challenging, especially on the buccal mucosa. Presentation of case: A 47-year-old man had a buccal mucosa mass for 10 years, which gradually grew over a year and irritated his chewing. A 2.2 ×2 cms buccal mass was observed with telangiectatic and erythematous alterations in the surrounding mucosa. The pre-operative tissue biopsy suggested salivary gland malignancy. The patient underwent surgical excision and a single-stage buccal advancement flap reconstruction, successfully closing the 4 cm defect. The final diagnosis was MEC ex pleomorphic adenoma. He reported mild discomfort during the first few months while opening his mouth. The patient had fully recovered after six months. Clinical discussion: This is the first case of MEC arising in a pleomorphic adenoma of the buccal mucosa. For low-grade and small-sized tumors, a single modality is appropriate for treatment. Local flaps such as buccal fat pad or musculomucosal flap can repair medium-sized defects. However, the buccal advancement flap provides effective functional and aesthetic benefits, optimal healing conditions, and reduces complications risk. Conclusion: The buccal advancement flap is a valuable option for reconstructing medium-sized buccal defects up to 4 cm. The single-stage surgical procedure has been proven to yield minimal complications and provide a favorable outcome.

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