Mucoepidermoid carcinoma of sublingual gland: a malignant neoplasm in an uncommon region

Kumar, Anil; Nair, Preeti P; Thomas, Shaji; Raman, Prabhu S; Bhambal, Annette M.

doi:10.1136/bcr.02.2011.3864

Cited by 11 publications

(1 citation statement)

References 7 publications

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“…Surgical excision of the tumour, through the means of a superficial parotidectomy, remains the cornerstone of treatment. While low-grade tumours are routinely amenable to local surgical resection, high-grade tumours are usually treated with a wide resection of the tumour [13].…”

Section: Discussionmentioning

confidence: 99%

Mucoepidermoid Carcinoma of the Parotid Gland Presenting as a Fungating Exophytic Mass: A Surgical Challenge Rooted in Extensive Nerve Encasement

Almas

Hussain

Ehtesham

et al. 2020

Cureus

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Parotid glands, which are predominantly composed of serous acini, are the largest salivary glands in the human body. Mucoepidermoid carcinoma (MEC) of the parotid gland is the most common parotid tumour that routinely presents as a painless, fixed mass below the ears. However, its presentation as a fungating mass remains exceedingly rare. Due to the intimate anatomical relationship between the parotid gland and the facial nerve, parotid malignancies can culminate in facial nerve palsy, posing an onerous surgical challenge. In this paper, we chronicle the case of a male who presented with a fungating/exophytic mass and facial nerve weakness. A superficial parotidectomy was performed, and the eventual histopathological workup divulged an advanced mucoepidermoid parotid carcinoma entirely encasing the marginal mandibular nerve. Consequently, the marginal mandibular nerve was sacrificed, alluding to the remarkable surgical challenge encountered. Clinically, this manifested as an impairment of the motor function in the patient's left lower lip.

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Section: Discussionmentioning

confidence: 99%

Mucoepidermoid Carcinoma of the Parotid Gland Presenting as a Fungating Exophytic Mass: A Surgical Challenge Rooted in Extensive Nerve Encasement

Almas

Hussain

Ehtesham

et al. 2020

Cureus

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NUT Midline Carcinoma of the Sublingual Gland: Clinical Presentation and Review

Seim

Philips

Schoenfield

et al. 2017

Head and Neck Pathol

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NUT midline carcinoma (NMC) is a rare and aggressive disease encountered in the midline of the head and neck or mediastinum. Due to its sparse incidence and subtle pathologic features, we aim to increase knowledge and awareness for this pathologic entity. We present an exemplary case of a young, healthy male presenting with oral cavity pain and cervical lymphadenopathy. This patient was initially diagnosed with an unspecified, highly aggressive sublingual gland malignancy and underwent locoregional resection with free flap reconstruction however suffered a rapid local recurrence and widely extensive metastasis within just 1 month. After rigorous analysis, final pathologic diagnosis revealed a poorly differentiated carcinoma with evidence of squamous differentiation that eventually, post-mortem tested positive for NMC. Only one prior case of sublingual gland NMC has been previously reported as we discuss the literature regarding all sublingual gland malignancies as well as the pathologic features and treatment options for NMC. We recommend consideration of testing for the NUT proto-oncogene at the time of biopsy in the clinical setting of a poorly differentiated midline carcinoma, especially with squamous differentiation, of the head or neck in order to identify patients for clinical trial enrollment and appropriately counsel on the poor clinical prognosis. Improving clinician awareness is critical to increase diagnostic accuracy and need to study prospective treatment outcomes as the first step toward improving management of this difficult disease.

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A case report of a sialolith proving difficult to locate, with a sudden urgency to rule out a mucoepidermoid carcinoma

2021

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Sialoliths are calcified masses that arise in salivary glands and ducts, which are usually composed of calcium and other mineral salts. Clinical presentation findings can include pain, swelling (usually associated with eating), obstruction of the salivary duct and sialadenitis. Approximately 80% of all sialoliths reported occur in the submandibular gland, whereas sublingual glands are rarely affected. 1 Giant sialoliths are defined as being greater than 15 mm in any one dimension and more than 1 g in weight. 2 Sialoliths arising extraductally are rarely reported, particularly when large in size. Here we report a large calcified mass presenting in the submandibular region which proved difficult to locate with imaging. CASE R EPORTA 71-year-old male was referred by his general dental practitioner to the Oral Surgery department regarding a 6-month history of a firm painful swelling in the left floor of mouth.

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Mucoepidermoid carcinoma of sublingual gland: a malignant neoplasm in an uncommon region

Cited by 11 publications

References 7 publications

Mucoepidermoid Carcinoma of the Parotid Gland Presenting as a Fungating Exophytic Mass: A Surgical Challenge Rooted in Extensive Nerve Encasement

Mucoepidermoid Carcinoma of the Parotid Gland Presenting as a Fungating Exophytic Mass: A Surgical Challenge Rooted in Extensive Nerve Encasement

NUT Midline Carcinoma of the Sublingual Gland: Clinical Presentation and Review

A case report of a sialolith proving difficult to locate, with a sudden urgency to rule out a mucoepidermoid carcinoma

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