Mucoepidermoid carcinoma of the bronchus in a 15‐year‐old girl with complex cytogenetic rearrangement involving 11q and over‐expression of cyclin D1

Barrett, Wade; Heaps, Luke St; Díaz, Sara; Sharma, Praveen; Arbuckle, Susan; Smith, Arabella

doi:10.1002/mpo.1367

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Cited by 7 publications

(1 citation statement)

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“…[2][3][4][5][6][7] Among many different types of tumors are benign (papilloma, hemangioma, leiomyoma), or malignant (mucoepidermoid carcinoma, adenoid cystic carcinoma / cylindroma, carcinoid). Early presenting symptoms often masquerade asthma.…”

Section: Brief Discussionmentioning

confidence: 99%

Not All That Wheezes Is Asthma—A Case Report of an Endobronchial Tumor in a Child

Moser¹,

Maggi²,

Bethencourt³

et al. 2004

Pediatric Asthma, Allergy & Immunology

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Section: Brief Discussionmentioning

confidence: 99%

Not All That Wheezes Is Asthma—A Case Report of an Endobronchial Tumor in a Child

Moser¹,

Maggi²,

Bethencourt³

et al. 2004

Pediatric Asthma, Allergy & Immunology

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Mucoepidermoid carcinoma of the lung arising at the primary site of a bronchogenic cyst: Clinical, cytogenetic, and molecular findings

Brassesco

Valera

Lira

et al. 2010

Pediatric Blood & Cancer

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Primary lung tumors are rare in children, and mucoepidermoid carcinoma (MEC) represents less than 10% of them. Additionally, MEC arising from bronchogenic cysts (BC) is particularly unusual. We describe the clinical and genetic findings on a MEC occurring within a previous location of a BC in an adolescent. This particular association has not been previously reported. The lesion revealed normal karyotype without the typical t(11;19)(q21;p13) translocation. Cyclin D1 overexpression (165-fold increase) was demonstrated by real-time PCR although FISH assessment showed normal hybridization at 11q13. Information on these unusual clinical presentations may present relevant insight on tumorigenesis of infrequent pediatric pulmonary tumors.

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Salivary Gland and Adnexal Type Tumors of the Lungs

Weissferdt

Moran

2012

Diagnostic Pathology of Pleuropulmonary Neoplasia

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Mucoepidermoid carcinoma of the bronchus in a 15‐year‐old girl with complex cytogenetic rearrangement involving 11q and over‐expression of cyclin D1

Cited by 7 publications

References 8 publications

Not All That Wheezes Is Asthma—A Case Report of an Endobronchial Tumor in a Child

Not All That Wheezes Is Asthma—A Case Report of an Endobronchial Tumor in a Child

Mucoepidermoid carcinoma of the lung arising at the primary site of a bronchogenic cyst: Clinical, cytogenetic, and molecular findings

Salivary Gland and Adnexal Type Tumors of the Lungs

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