Mucoepidermoid Carcinoma of the Eyelid Skin

Zhang, Cheng; Ticho, Karl E.; Ticho, Benjamin H.; Edward, Deepak P.; Yan, Xiaoming; Tso, Mark O.M.

doi:10.1097/00002341-199909000-00013

Cited by 7 publications

(6 citation statements)

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“…lung, bladder), where focal mucin production does not qualify as adenocarcinoma 7 . Mucoepidermoid carcinoma should contain well‐differentiated squamous cells with rare keratinization, mucus‐secreting globet cells and intermediate cells 1,8–10 . Finally, we would like to emphasize the need to exclude a metastatic visceral carcinoma before considering this unusual primary skin tumor.…”

Section: Discussionmentioning

confidence: 98%

Primary cutaneous adenosquamous carcinoma: a case report and review of the literature

Azorín

López‐Ríos²,

Ballestı́n³

et al. 2001

J Cutan Pathol

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Section: Discussionmentioning

confidence: 98%

Primary cutaneous adenosquamous carcinoma: a case report and review of the literature

Azorín

López‐Ríos²,

Ballestı́n³

et al. 2001

J Cutan Pathol

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“…A relatively early diagnosis of an MEC lesion with a 20 months history and aggressive treatment with a combination of exenteration of the orbit and irradiation led to an absence of recurrence at two-and-a-half year follow-up as reported by Vogel et al [ 11 ]. Similarly, early diagnosis of a MEC lesion with only a few weeks history of a relatively small neoplasm was treated with local surgical resection, leading to an absence of recurrence at 1 year follow-up as reported by Zhang et al [ 10 ]. As reported by Nouri et al [ 9 ] and in our current report, Mohs micrographic surgery with identification of negative margins of relatively small MEC lesions, followed by oculoplastic reconstructive surgery has allowed for the longest reported remission (3 and 4 years, respectively) and achievement of good functional and aesthetic results.…”

Section: Discussion/conclusionmentioning

confidence: 92%

“…Only 9 reports of primary cutaneous MEC of the eyelid have been previously documented in the literature, with our patient representing only the tenth reported case of its kind [7][8][9][10][11][12][13][14][15]. These cases, along with the case we present here, have been summarized and shown in Table 1, emphasizing initial presentation of the MEC lesion, time to initial presentation, treatment strategy utilized, recurrence status, time of follow-up, presentation during time of recurrence, and any other consequences of the treatment approach utilized.…”

Section: Discussion/conclusionmentioning

confidence: 99%

A Rare Case of Cutaneous Mucoepidermoid Carcinoma of the Eyelid: A Case Report and Literature Review

Abrou

Abowd

2021

Case Rep Ophthalmol

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Mucoepidermoid carcinoma (MEC) is most commonly found to affect the salivary glands and rarely affects other organ systems. In this report, we present an especially rare case of cutaneous MEC affecting the eyelid. A 72-years-old female patient presented with a painless, cyst-like, progressively enlarging lesion of the left upper eyelid. Biopsy revealed characteristic features of MEC, including a mixture of mucus-secreting cells and epidermoid cells. The 3 mm MEC lesion was excised by Mohs micrographic surgery, leaving a 0.8 × 1.1 cm eyelid defect that was repaired by oculoplastic reconstruction. To date, the patient has been in remission for 4 years with good functional and aesthetic outcomes. This case represents the longest reported remission among only 9 previously reported cases of cutaneous MEC of the eyelid and highlights the therapeutic and aesthetic efficacy of Mohs micrographic surgery. We also offer a literature review of the 9 previously reported cases of eyelid MEC and a discussion of patient presentation, treatment comparisons, remission success, and key points in the management of MEC of the eyelid.

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“…Reported cases in the English literature are summarized [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] (Table 1). Reported cases in the English literature are summarized [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15][16][17][18] (Table 1).…”

Section: Discussionmentioning

confidence: 99%

Primary Cutaneous Versus Salivary Gland Origin Mucoepidermoid Carcinoma

Salama

Alowami

2015

The American Journal of Dermatopathology

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Mucoepidermoid carcinoma (MEC) is a malignant glandular epithelial neoplasm that most commonly arises in the major salivary glands. Primary cutaneous MEC is very rare. There is a particular diagnostic challenge in determining the primary site of MEC when it is found in skin overlying the parotid gland. Attention to a combination of morphologic findings may be helpful. However, differentiation of primary cutaneous MEC from secondary cutaneous involvement by a parotid MEC may be unnecessary once the parotid gland is infiltrated. We report the case of a 54-year-old male with a 2-cm asymptomatic mass overlying the right parotid gland, which was managed by excision of the affected skin, right total parotidectomy, and right neck dissection. Histopathologic and immunohistochemical findings were consistent with a cutaneous intermediate-grade MEC. Postoperative radiotherapy was deferred. The patient showed no evidence of recurrence or metastasis at 2 months before self-discontinuing follow-up. To our knowledge, this is only the second reported case of MEC involving the parotid gland, but of overlying primary cutaneous origin.

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Mucoepidermoid Carcinoma of the Eyelid Skin

Cited by 7 publications

References 0 publications

Primary cutaneous adenosquamous carcinoma: a case report and review of the literature

Primary cutaneous adenosquamous carcinoma: a case report and review of the literature

A Rare Case of Cutaneous Mucoepidermoid Carcinoma of the Eyelid: A Case Report and Literature Review

Primary Cutaneous Versus Salivary Gland Origin Mucoepidermoid Carcinoma

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