Mucoepidermoid Carcinoma of the Eyelid: A Rare Presentation

Akhtar, Kafil

doi:10.24966/inid-8654/100020

Cited by 1 publication

(2 citation statements)

References 15 publications

(28 reference statements)

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“…Our patient presented with a relatively small, cyst-like lesion that could be partially transilluminated and was marked by a small amount of blood or hyperpigmentation on the inferior aspect of the lesion. Histologically, it has been previously established that MEC is characterized by a mixture of epidermal cells and mucus-secreting cells and has also previously been reported to be immunohistochemically positive for carcinoembryonic antigen as in our patient's case as well [10,12,15]. Therefore, awareness of this condition and the wide range in presentation when considering a differential diagnosis may help lead to successful diagnosis and timely treatment.…”

Section: Discussion/conclusionsupporting

confidence: 63%

“…Only 9 reports of primary cutaneous MEC of the eyelid have been previously documented in the literature, with our patient representing only the tenth reported case of its kind [7][8][9][10][11][12][13][14][15]. These cases, along with the case we present here, have been summarized and shown in Table 1, emphasizing initial presentation of the MEC lesion, time to initial presentation, treatment strategy utilized, recurrence status, time of follow-up, presentation during time of recurrence, and any other consequences of the treatment approach utilized.…”

Section: Discussion/conclusionmentioning

confidence: 99%

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A Rare Case of Cutaneous Mucoepidermoid Carcinoma of the Eyelid: A Case Report and Literature Review

Abrou

Abowd

2021

Case Rep Ophthalmol

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Mucoepidermoid carcinoma (MEC) is most commonly found to affect the salivary glands and rarely affects other organ systems. In this report, we present an especially rare case of cutaneous MEC affecting the eyelid. A 72-years-old female patient presented with a painless, cyst-like, progressively enlarging lesion of the left upper eyelid. Biopsy revealed characteristic features of MEC, including a mixture of mucus-secreting cells and epidermoid cells. The 3 mm MEC lesion was excised by Mohs micrographic surgery, leaving a 0.8 × 1.1 cm eyelid defect that was repaired by oculoplastic reconstruction. To date, the patient has been in remission for 4 years with good functional and aesthetic outcomes. This case represents the longest reported remission among only 9 previously reported cases of cutaneous MEC of the eyelid and highlights the therapeutic and aesthetic efficacy of Mohs micrographic surgery. We also offer a literature review of the 9 previously reported cases of eyelid MEC and a discussion of patient presentation, treatment comparisons, remission success, and key points in the management of MEC of the eyelid.

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Section: Discussion/conclusionsupporting

confidence: 63%