Mucoepidermoid lung carcinoma in a pediatric patient confused with pneumonia

Tri, Tran Thanh; Vu, Le Thuong; My, Thieu-Thi Tra; Thach, Pham Ngoc; Duc, Nguyen Minh

doi:10.1016/j.radcr.2021.06.078

Cited by 6 publications

(4 citation statements)

References 12 publications

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“…Of the 27 patients in this study, 20 patients were young or middle-aged, with the median age being 42. Young and middle-aged patients often show symptoms in the airways [ 4 , 5 ], while elder patients often show symptoms in the periphery of the lung, the difference being statistically significant and close to the report of Han[ 1 ] et al. It is usually believed that the onset of this disease shows no gender difference, but Zhuang Wu et al.…”

Section: Discussionsupporting

confidence: 69%

MSCT findings of primary Pulmonary mucoepidermoid carcinoma

Liu,

Nie

2023

Annals of Medicine

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Objectives To improve diagnostic accuracy of pulmonary mucoepidermoid carcinoma (PMEC) through multi-detector computed tomography (MSCT) findings. Methods MSCT findings of 27 histopathologically confirmed PMEC cases were retrospectively analyzed, including the location, size, margin, density, enhancement of the lesion and accompanying signs. Results Among the 27 PMEC cases, 6 (6/27, 22.2%) were the large airway pattern, 14 were (14/27, 51.9%) the pulmonary hilum pattern, and 7 (7/27, 26.9%) were the peripheral pattern. Among those 20 cases with central pattern(6 large airway and 14 pulmonary hilum patterns), 6 presented mild enhancement, 4 moderate enhancement, 5 severe enhancement, 5 heterogeneous enhancement, and 3 with calcification. 7 cases with peripheral patterns were presented as solid pulmonary nodules and masses, 3 with severe enhancement, 1 with moderate enhancement and 3 with mild enhancement. Four cases accompanied by lymph nodal metastasis, and 7 cases with distant organ metastasis. Age( t = –3.132, p = 0.005), enlarged lymph node ( x 2 = 9.281, p = 0.005), and distant metastasis( x 2 = 7.816, p = 0.008) were statistically significant in the low-grade group and high-grade group. Conclusions MSCT images of PMEC patients demonstrated some characteristic findings, which would help improve the diagnostic accuracy of the disease.

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Section: Discussionsupporting

confidence: 69%

MSCT findings of primary Pulmonary mucoepidermoid carcinoma

Liu,

Nie

2023

Annals of Medicine

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“…Recognizing the functions of radiography, CT 16 and 18 F-FDG PET in the evaluation of pulmonary masses in children, may lead to the routine use of 18 F-FDG PET in confirming suspected cases of MEC in pediatric patients, resulting in earlier diagnoses, more accurate staging, and better patient outcomes. However, caution should be exercised to differentiate malignant from benign lesions because of the frequency of false-positive results in active inflammatory foci and false-negative results in small malignant lesions 7 .…”

Section: Discussionmentioning

confidence: 99%

Pulmonary mucoepidermoid carcinoma in children: a rare diagnosis not to be overlooked – case report

Dardouri¹,

Ezzine²,

Fredj³

et al. 2023

Annals of Medicine &Amp; Surgery

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Introduction and importance: Pulmonary mucoepidermoid carcinoma (PMEC) in children is a rare entity. The diagnosis is often unrecognized, often treated as pneumonia, a more frequent diagnosis at this age. Case presentation: The authors report in this article, the case of a 12-year-old child with a clinical history of chronic cough evolving for 6 months with recurrent episodes of pneumonia. The presence of a foreign body was suggested on the thoracic computed tomography (CT). PMEC was histopathologically determined on biopsy. Fluorine- 18 -fluorodesoxyglucose positron emission tomography ( 18 F-FDG PET)/CT was performed as part of the extension work-up prior to surgical management. Clinical discussion: Preoperative imaging with 18 F-FDG PET/CT seems to be a valuable tool for predicting tumor grade, nodal stage, and postsurgical prognosis in mucoepidermoid carcinoma. PMEC patients with high 18 F-FDG PET/CT uptake may need extensive mediastinal lymph node dissection and adjuvant therapy. Conclusion: PMEC has different presentations depending on the degree of tumor differentiation on PET/CT whose input in the management of these rare cancers requires further studies.

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“…Distant metastases is rare [ 5 ] but lymph node metastasis has been reported, prompting the need for chemotherapy [ 12 ]. One of our patients had radiotherapy to the local area because his tumour was high grade.…”

Section: Discussionmentioning

confidence: 99%