Mucormicose de seios paranasais e órbitas em paciente imunocompetente: relato de caso e revisão de literatura

Santana, Nícia O. R.; Kehrle, Helga Moura; Faria, Isnaldo P. de; Estrella, Cláudio N.

doi:10.1590/s0034-72992001000500020

Cited by 5 publications

(7 citation statements)

References 5 publications

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“…Magnetic resonance imaging (MRI) is a very useful technique for detecting potential intradural and intracranial extensions. Perineural presence can be shown by a contrast-enhanced MRI [19]. After all, it is very possible for patients at an early stage of the disease to have regular imaging scans, which reinforces that a surgical procedure with early biopsies, if there is clinical suspicion, is necessary for a correct diagnosis.…”

Section: Discussionmentioning

confidence: 88%

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Fatal rhinocerebral mucormycosis in diabetic patients: report of two cases

Gomes

Correia

Freitas

et al. 2021

Preprint

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Mucormycosis is a potentially serious and quite rare fungal infection, caused by the Saprophytic fungus, of the order Mucorales, Absidia, Mucor, Rhizomucor and Rhizopus. These agents are commonly isolated from decomposing soil and plant material and remain dormant in healthy individuals in the respiratory and digestive tubes when inhaling or ingesting contaminated food. It becomes pathogenic when the individual gets immunocompromised and debilitated, progressing to an aggressive and often lethal clinical picture, which requires accurate diagnosis and prompt treatment. There are reports in the literature of its gastrointestinal, pulmonary, cutaneous, rhino-orbital-cerebral, endocardial and osteoarticular forms. Regardless of its location, treatment necessarily includes early clinical diagnosis, stabilization of systemic comorbidities and aggressive drug and surgical therapy, resulting in a mortality rate of up to 40% of cases. It is a relevant topic in tertiary care hospitals in terms of contamination, being a matter of concern if present in premature newborns and burn therapy units. The purpose of this article is to report a case of rhino-orbital-cerebral Mucormycosis acquired in the community by a decompensated diabetic patient who evolved with invasion of the hard palate, paranasal sinuses, orbits and cavernous sinus, spreading to the central nervous system and leading to thrombosis the cavernous sinus.

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Section: Discussionmentioning

confidence: 88%

“…Cerebral involvement is characterized by changes in the state of consciousness, which can cause seizures and/or hemiplegia. If occurs invasion of the cavernous sinus, fungal aneurysms of the internal carotid artery are common and generally fatal [19].…”

Section: Disclosures and Declarationsmentioning

confidence: 99%

Fatal rhinocerebral mucormycosis in diabetic patients: report of two cases

Gomes

Correia

Freitas

et al. 2021

Preprint

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“…Rios-Gonçalves et al 19 , em 1991, acompanharam dois pacientes diabéticos com quadros clínicos semelhantes ao da nossa paciente e que, com a mesma conduta, conseguiram êxito no tratamento. Também Santana et al 8 , da mesma forma, divulgaram caso de mucormicose dos seios paranasais e orbitais com bom resultado. Segundo Mileshkin et al, uma alternativa é a anfotericina B lipossomal, com menos toxicidade permitindo atingir doses mais elevadas 21 .…”

Section: Discussionunclassified

“…Embora muito mais comum em pacientes com deficiência imunológica, a mucormicose pode afetar indivíduos sãos, como relataram Santana et al 8 .…”

Section: Introductionunclassified

Mucormicose rinocerebral: apresentação de caso com sobrevida e revisão de literatura

Xavier¹,

Korn²,

Granato³

2004

Rev. Bras. Otorrinolaringol.

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“…In this case, surgical intervention and systemic treatment with Amphotericin B were necessary to control the infection. However, there are researchers who alert to the possibility that the fungus additionally affects immonocompetent individuals (Santana et al, 2001).…”

Section: Figurementioning

confidence: 99%

Identification of keratinophilic fungi in the coat microbiota of anteaters retained in captivity in two Brazilian Zoos

Bentubo

Moreira

Paula

et al. 2022

RSD

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Anteaters comprise three different species: Myrmecophaga tridactyla (flag anteater), Tamandua tetradactyla (mini anteater) and Cyclopes didactylus (anteater), some considered vulnerable to extinction. These species are distributed over a large part of the Brazilian territory, especially in the cerrado biome. In order to preserve these species, some research work on the health status of these animals has been carried out, both in captive and free-living animals. The objective of this study was to investigate keratinophilic filamentous fungi, including dermatophytes, in the coat of 27 adult anteaters retained in captivity. Among the animals studied, 14 were giant anteater (Myrmecophaga tridactyla) and 13 were small anteater (Tamandua tetradactyla). These specimens were retained at the São Paulo Zoological Park Foundation and Quinzinho de Barros Municipal Zoological Park. Samples were obtained by means of rubbing sterilized squares of carpet on the coat of each animal. Each carpet was seeded in Petri dishes containing Mycobiotic™ agar medium (Difco™) and incubated at 25ºC until colony growth was observed. Dermatophytes were not isolated; however, the following genera of filamentous fungi were identified: Cladosporium spp. (51.8%), Scopulariopsis sp (29.6%), Aspergillus spp. (22.2%), Acremonium spp. and Chrysosporium spp. (11.1%) and Mucor spp. (7.4%), among these we highlight the keratinophilics: Scopulariopsis sp, Acremonium spp. and Chrysosporium spp. There are few studies on the prevalence of dermatophytes and other keratinophilics in wild animals and none on anteaters. It was possible to confirm the presence of non-dermatophytic keratinophilics in the normal microbiota of anteaters, similarly to what was observed in other mammals.

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Mucormicose de seios paranasais e órbitas em paciente imunocompetente: relato de caso e revisão de literatura

Cited by 5 publications

References 5 publications

Fatal rhinocerebral mucormycosis in diabetic patients: report of two cases

Fatal rhinocerebral mucormycosis in diabetic patients: report of two cases

Mucormicose rinocerebral: apresentação de caso com sobrevida e revisão de literatura

Identification of keratinophilic fungi in the coat microbiota of anteaters retained in captivity in two Brazilian Zoos

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