Mucosa-associated lymphoid tissue of nasopharynx: A case report and literature review

Tang, Tianci; Ni, Xiaochen; Song, Xinmao

doi:10.1016/j.radcr.2022.05.087

Radiology Case Reports

2022

DOI: 10.1016/j.radcr.2022.05.087

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Mucosa-associated lymphoid tissue of nasopharynx: A case report and literature review

Tianci Tang

Xiaochen Ni

Xinmao Song

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2023

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Low-grade malt lymphoma of the nasopharynx in young adults: Successful treatment of a rare diagnosis at a rare site by radiotherapy

Singh,

Bhatnagar,

Bisht

et al. 2023

Journal of Cancer Research and Therapeutics

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Introduction: Mucosa Associated Lymphoid Tissue (MALT) lymphoma is the third most common subgroup of Non-Hodgkin’s lymphoma and is the most common type of primary extranodal lymphoma. They are rarely found in the nasopharyngeal region and their mean age at presentation is the sixth decade of life. Materials and Methods: We present the clinical, pathological, treatment and 5-year follow-up data of 5 cases of nasopharyngeal MALT lymphoma treated with definitive radiotherapy at our hospital, between 2009 and 2011. Results: The average age of diagnosis was 27 years which is more than a decade earlier than what has been reported previously. Clinical symptoms included nasal obstruction, tinnitus and hearing loss. All five patients had locoregional disease. They were treated by definitive radiotherapy to a dose between 30 to 40 Gy. At 5 years of follow-up, 4 patients were in complete remission while one had disease relapse. Conclusion: The younger age of presentation compared to older reports in this rare subsite was an interesting finding in our study. The authors speculate that rising levels of particulate air pollution may have played a part in the etiology in this younger population. Our series shows that despite the younger age, the disease displays an indolent course and responds well to radiotherapy alone as the primary treatment. Recurrence or disseminated disease is also highly treatable with systemic chemotherapy.

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Low-grade malt lymphoma of the nasopharynx in young adults: Successful treatment of a rare diagnosis at a rare site by radiotherapy

Singh,

Bhatnagar,

Bisht

et al. 2023

Journal of Cancer Research and Therapeutics

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show abstract

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Mucosa-associated lymphoid tissue of nasopharynx: A case report and literature review

Cited by 1 publication

References 30 publications

Low-grade malt lymphoma of the nasopharynx in young adults: Successful treatment of a rare diagnosis at a rare site by radiotherapy

Low-grade malt lymphoma of the nasopharynx in young adults: Successful treatment of a rare diagnosis at a rare site by radiotherapy

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