“…Chronic anal fissure (CAF) is common and affects all age groups with an equal incidence in both genders [1]. Surgery, including lateral internal sphincterotomy, anal stretch, posterior sphincterotomy, fissurectomy, dermal advancement flap and autologous fat transplantation, is potentially associated with risk of a transient continence disturbance [2][3][4][5][6][7][8][9][10]. Pharmacological agents, such as glyceryltrinitrate (GTN), diltiazem (DTZ) and botulinum injection, can be successful treatments but they have a significant recurrence rate [11][12][13][14][15].…”