Mucosal Melanomas: A Review

Batsakis, John G.; Suarez, Patricia

doi:10.1097/00125480-200007030-00006

Cited by 73 publications

(48 citation statements)

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“…Mucosal melanomas of the head and neck are very rare, representing about 0.4-1.8% of all malignant melanomas [4]. These tumors originate from the melanocytes present in the mucous membranes; however, the risk factors for cutaneous melanomas (e.g., sun exposure) do not apply for mucosal tumors [4,5].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Jain

Priya

Kumar³

2012

Indian J Otolaryngol Head Neck Surg

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We report a case of melanocarcinoma of sinonasal region in a 42 year old female who presented with brownish-colored sino-nasal mass involving left orbit, spontaneous epistaxis, facial swelling on left side, and ulceration of overlying skin, cervical and distant metastasis in liver over a short time span of 3 months. On biopsy, the mass was diagnosed as melanocarcinoma of nose and paranasal sinuses. Primary mucosal malignant melanoma of the nasal cavity, paranasal sinuses, and nasopharynx is an aggressive disease and fortunately rare with current research data being mainly from western populations. The disease is known to be more common among elderly population in their seventies and to follow a prolonged course due to innocuous symptoms. This case is being reported for its rarity in our geographical region, early age of presentation and rapid progression of the disease over a span of 3 months.

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Section: Discussionmentioning

confidence: 99%

“…These tumors originate from the melanocytes present in the mucous membranes; however, the risk factors for cutaneous melanomas (e.g., sun exposure) do not apply for mucosal tumors [4,5]. Melanocytes are widely distributed throughout cutaneous and mucosal surfaces.…”

Section: Discussionmentioning

confidence: 99%

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Jain

Priya

Kumar³

2012

Indian J Otolaryngol Head Neck Surg

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“…The urethra, particularly the distal urethra including fossa navicularis and urethral meatus are the most common locations and about 30% of patients already harbor metastasis at the time of diagnosis with dangerous boundaries with regards to the depth of invasion and size of the tumor mass. 57,58 While cancers of the anterior urethra preferentially infiltrate into superficial inguinal lymph nodes, those involving the posterior urethra generally infiltrate into pelvic lymphatic channels. 57 However, the presence or absence of lymph node metastasis is the most significant prognostic factor for survival, as survival rates are approximately halved by the presence of nodal metastasis.…”

Section: ! "mentioning

confidence: 99%

Malignant Melanoma in Genito-Urinary Tract

Tepeler¹,

Erdem²,

Onol³

et al. 2011

Melanoma in the Clinic - Diagnosis, Management and Complications of Malignancy

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“…In general, the mucosal melanomas are also more refractory to therapeutic modalities. In part, this may be due to anatomic restrictions of site and the large size of tumor when first discovered (4).…”

Section: Malignant Melanoma Etiology Risk Factorsmentioning

confidence: 99%