Mucous Gland Adenoma of Bronchus: Report of a Case with Histochemical Study of Secretion

Gilman, Richard A.; Klassen, Karl P.; Scarpelli, Dante G.

doi:10.1093/ajcp/26.2.151

Cited by 26 publications

(5 citation statements)

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“…The atypical carcinoid was first described in 1944 (Engelbreth-Holm, 1944) and the muco-epidermoid adenoma in 1945 (Smetana, Iverson, and Swan, 1952), and in 1956 a further variety, the cystadenoma or bronchial mucous gland adenoma, was added (Gilman, Klassen, and Scarpelli, 1956).…”

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confidence: 99%

Bronchial adenoma: review of 18-year experience at the Brompton Hospital.

Lawson¹,

Ramanathan²,

Hurley³

et al. 1976

Thorax

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When adding 22 cases of bronchial adenomata seen in the Brompton Hospital to the more than 100 cases previously documented, Foster-Carter (1941) stated that no death had ever been recorded from malignant change in a bronchial adenoma. Price-Thomas (1954), reporting a personal series of 41 bronchial adenomata treated in the Brompton and Westminster Hospitals, concluded that 'the incidence of malignancy is so low that it is possible for practical purposes to ignore it'. More recent papers have, however, questioned the use of the term bronchial adenoma, emphasizing not only the varying behaviour of the four tumour types included in the term-the bronchial carcinoid, the adenoid cystic carcinoma (cylindroma), the muco-epidermoid tumour, and the true bronchial mucous gland adenoma-but also the differing degrees of malignancy of the bronchial carcinoid itself (Donahue, Weichert, and Ochsner, 1968;Meffert and Lindskog, 1970;Tolis et al., 1972;Turnbull et al., 1972). In a Mayo Clinic series of 215 cases of bronchial carcinoid (Arrigoni, Woolner, and Bernatz, 1972), 23 (11%) were considered to have atypical histological features and, of these, 70% metastasized and 30%/O were dead after a mean survival of 27 months. This is to be contrasted with the usual bronchial carcinoid five-year survival of 80% or more (Overholt, Bougas, and Morse, 1957; Donahue et al., 1967). 245 on 7 May 2018 by guest. Protected by copyright.

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mentioning

confidence: 99%

Bronchial adenoma: review of 18-year experience at the Brompton Hospital.

Lawson¹,

Ramanathan²,

Hurley³

et al. 1976

Thorax

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“…Mucous gland adenoma (MGA) are rare tumors originating from mucous-secreting glands, mainly from the large airway mucosa. Most arise from the main, lobar, or segmental bronchi and rarely from the trachea (8,9). Pathologically, MGAs consist of mucus-secreting components of tracheobronchial seromucinous glands, typically presenting as an endobronchial, multicystic, well-circumscribed tumor (10).…”

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confidence: 99%

A Twelve-Year-Old-Girl with Intra-Tracheal Mucous Gland Adenoma: A Case Report

Khanbabaee,

Safapour,

Taghizadeh Herat

et al. 2024

J Compr Ped

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Introduction: Tracheal tumors are rare in the pediatric population. Primary tumors within the trachea often present with non-specific symptoms during the initial stages, leading to a delayed diagnosis. Prompt diagnosis of a tracheal tumor is crucial due to the risk of life-threatening airway obstruction it poses. This article discusses the case of a twelve-year-old girl who experienced 8years of breathing difficulties without an adequate response to treatment. Case Presentation: The patient was referred to Mofid Children's Hospital after experiencing 8 years of difficulty with dyspnea. Her dyspnea was classified as functional class 2 and was accompanied by dry coughs. Additionally, a biphasic stridor was observed during her auscultation. Further investigations revealed an intra-tracheal mass, identified as a mucous gland adenoma (MGA). Imaging and pathology showed no signs of malignancy. Following her surgery, she was completely free of symptoms, and her follow-up spirometry showed no abnormalities. Conclusions: In this article, we present a detailed case of MGA. Despite the low incidence of intra-tracheal tumors, conducting further studies in patients who respond poorly to treatment is crucial. The potential complications from these tumors can be catastrophic. Thus, enhancing our knowledge and expertise in this area is of great importance.

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“…Endobronchial lesions in the main, lobar, segmental, or subsegmental bronchus are a common presentation [4]. This tumor was first reported in 1882 by Muller as a pathologic entity separate from carcinoma of the lung and was first named bronchial adenoma arising from mucous gland [5]. Peripheral tumors, presenting with an asymptomatic pulmonary nodule, occur in 20% of the cases and tracheal occurrences have been reported, although rarely.…”

Section: Discussionmentioning

confidence: 99%

Bronchial Adenoma Masquerading as Pneumonia: A Rare Case Report

Kumar

Kumar²,

Sharma³

et al. 2017

IJCR

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A 29-year old non-smoker woman presented with breathlessness, cough with minimal expectoration and hemoptysis. Serial chest X-rays were suggestive of progressive collapse of right lung field. CECT chest revealed large endobronchial lesion in right main bronchus and obstructive collapse consolidation of right lower lobe and part of the middle lobe. Fiberoptic bronchoscopy revealed an endobronchial mass obstructing the right main bronchus. This reddish polypoid mass bleed on touch that was suggestive of bronchial adenoma and it was confirmed by histopathological examination. Patient was treated empirically with anti-tubercular drugs due to high prevalence of tuberculosis in our setting; however, the patient had clinical deterioration. Following the histopathology report, the diagnosis of bronchial adenoma was established. Bronchial adenoma should be considered in a young female patient presenting with hemoptysis and obstructive pneumonia.

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Mucous Gland Adenoma of Bronchus: Report of a Case with Histochemical Study of Secretion

Cited by 26 publications

References 0 publications

Bronchial adenoma: review of 18-year experience at the Brompton Hospital.

Bronchial adenoma: review of 18-year experience at the Brompton Hospital.

A Twelve-Year-Old-Girl with Intra-Tracheal Mucous Gland Adenoma: A Case Report

Bronchial Adenoma Masquerading as Pneumonia: A Rare Case Report

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