Mud therapy and skin microbiome: a review

Antonelli, Michele; Donelli, Davide

doi:10.1007/s00484-018-1599-y

Cited by 23 publications

(8 citation statements)

References 67 publications

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“…The mud can affect the microbiology of the skin, which has a beneficial effect on immune function (5 in vitro studies so far). Therefore, it would be important to investigate the interaction of different muds with the microbiome of the skin in order to better characterize their properties [ 39 , 40 ]. A portion of mud extracts inhibited the expression of VCAM-1 by endothelial cells and reduced monocyte adhesion to activated endothelial cells, which means an anti-inflammatory effect [ 41 ].…”

Section: Discussionmentioning

confidence: 99%

The Effects of Lakitelek Thermal Water and Tap Water on Skin Microbiome, a Randomized Control Pilot Study

Bender¹,

Gabriella²,

Kristóf³

et al. 2023

Life

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The beneficial effects of balneotherapy have been proven by numerous clinical studies on locomotor disorders. To date, there is only scant data on changes in the microbiome system of the skin during balneotherapy. The aim of this study was to compare the effects of thermal water and tap water on the skin’s microbiome in healthy volunteers. 30 healthy female volunteers participated in the study. The experimental group (of 15 women) spent 30-min 10 times, in Gabriella Spring’s thermal baths (i.e., mineral water containing sodium hydrogen carbonate).The controlled group (15 women) had the same, but in tap water. The results of this study have proven that there is a difference in the influencing effects of tap water and medicinal water on the microbiome of the skin. After bathing in the thermal water of Lakitelek, Deinococcus increased significantly at the genus level, and the tendency for Rothia mucilaginosa bacteria also increased. At the species level, Rothia mucilaginosa increased significantly, while Paracoccus aminovorans and the tendency for Paracoccus marcusii decreased. When the values of the two trial groups after bathing at the genus level were compared, Rothia bacteria increased significantly, while Haemophilus tended to increase, Pseudomonas tended to decrease, Neisseria tended to increase significantly, and Flavobacterium tended to decrease. At the species level, Geobacillus vulcani decreased significantly, and the tendency for Burkholderia gladioli decreased. The growth of Rothia mucilaginosa and the decrease in the tendency of Paracoccus, Pseudomonas, Flavobacteroium, and Burkholderia gladioli confirm the beneficial effect of balneotherapy. In this study, trends are represented by the uncorrected p value. The main result was that the thermal water changed certain bacteria of the skin, both on the genus and species levels, but there were no significant changes in the tap water used, either at the genus or species level. We first compared the worlds of thermal water and tap water’s microbiome systems. The thermal water decreased the number of certain inflammatory infectious agents and could enhance some of their positive effects, which have been proven at the molecular level. Our results can provide an important clue in the treatment of certain skin diseases. The research of the skin microbiome during balneotherapy can be one of the most intriguing and exciting topics of the future and can bring us closer to understanding the mechanism of action of balneotherapy.

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Section: Discussionmentioning

confidence: 99%

The Effects of Lakitelek Thermal Water and Tap Water on Skin Microbiome, a Randomized Control Pilot Study

Bender¹,

Gabriella²,

Kristóf³

et al. 2023

Life

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“…Dermal microbiological studies suggest that skin microbiome can have a role in influencing infections, inflammatory illnesses, autoimmune disorders, as well as neoplasms (Antonelli and Donelli 2018). In conclusion, the microbiome of spa waters and human skin have public health significance; if disturbing, in our present knowledge, the consequences cannot be assessed.…”

Section: Self-preservation Of Microbiological Quality: Spa Water As Amentioning

confidence: 90%

To treat or not to treat? Misbeliefs in spa water disinfection

Varga

2019

Int J Biometeorol

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Spa waters should be left untreated" says the dogmatic approach. Health authorities of European countries having traditional spa culture strictly control hygienic conditions of bathing in thermal/mineral waters. These regulations are based on the assumption that chemical treatment (disinfection) of such waters impacts their healing effects. However, a slow change of paradigm has been observed in studying the mode of action of spa waters that could help overcome recent attitudes. Organic content or the role of microbiome has also been emphasized by some authors recently. The article deals with possible interactions among aquatic microorganisms and the disinfection and health effects of spa waters and tries to explain the new findings in this field.

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“…The obtained result is presented in the form of the physicochemical analysis bulletin. When applying peloids, a series of processes take place at the level of the skin:  sensitive reception of mud qualities/properties and their transmission to the upper stages of integration and control;  exchange of energy and substance with the peloid environment;  fulfillment of adaptive functions: circulatory (peripheral circulation of thermoregulation), secretory (sweating), protective (keratinogenesis, melanogenesis, hydrolipid film formation);  integration of skin -mud application effects in the general physiology of the body: thermoregulation, vitamin D synthesis, optimization of homeostatic balances: immune, endocrine, and neurovegetative of the body (17).…”

Section: Pharmacodynamic Propertiesmentioning

confidence: 99%

“…The complex interdisciplinary characterization of the natural therapeutic factors necessarily includes interpretation of physicochemical analyzes and microbiological (15)( 16) examinations. Classification of muds (17) Clay (18) has been used by humans since before recorded history to accomplish basic but fundamental healthcare purposes. The clay plates of Nippur, Mesopotamia, which date back to about 2500 BC, contain a reference to the use of clays for therapeutic purposes, including the treatment of wounds and the inhibition of hemorrhages.…”

Section: Introductionmentioning

confidence: 99%

Mud therapy and rehabilitation - scientific relevance in the last six years (2015 – 2020) Systematic literature review and meta-analysis based on the PRISMA paradigm

Munteanu¹,

Rotariu

Dogaru

et al. 2020

Balneo and PRM Research Journal

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Background. Balneotherapy is a stimulation - adaptation treatment method applied in the forms of bathing, drinking, and inhalation cures performed with natural therapeutic factors, a method which is acting in three main ways: thermally, mechanically, and chemically. Mud or peloids are natural therapeutic factors formed by natural processes under the influence of biological and geological phenomena, which in a finely dissolved state and mixed with water (mud) are used in medical practice in the form of baths or local procedures. Objective. This systematic review aims to rigorously select related articles and identify within their content, the main possible uses of therapeutic mud and physiological mechanisms, to see the main region of scientific interest for pelotherapy, and to discuss the value of mud therapy in rehabilitation medicine. Methods. The working method is based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. We searched for open-access articles published in English, between January 2015 and December 2020, from the following databases: Cochrane, Elsevier, NCBI/PubMed, NCBI/PMC, PEDro, and ISI Web of Knowledge/Science (the latter was also used to identify ISI indexed articles). The contextually searched syntax used was ”Pelotherapy/Peloidotherapy/Mud-therapy/ /Fango-therapy AND Rehabilitation”. The selected articles were analyzed in detail regarding pathologies addressed by mud therapy and country scientific relevance for this therapeutic method. The meta-analysis proceeded was designated to estimate the prevalence of various pathologies in the use of mud therapy. Results. Our search identified, first, 394 articles. Based on the successive filtering stages and, respectively, on the classification criteria of the Physiotherapy Evidence Database (PEDro), we finally identified/retained and analyzed 68 articles. Although, in principle, a rigorous method – and we have followed the PRISMA type paradigm – there still might be some missing works of our related article selection. On the other hand, to augment/ consolidate our documentation base, we have used also 40 papers freely found in the literature, and even – aiming, too, at an as exhaustive knowledge underpinning as possible – derogatively, we have also considered some articles which, probably being very new, couldn't yet have reached the PEDro threshold score we have settled. Conclusions. This paper overviews the current state-of-the-art knowledge in the approach of peloidotherapy in rehabilitation, with a focal point on the therapeutic properties of peloids. Keywords: mud-therapy, pelotherapy, peloidotherapy, fango therapy, rehabilitation, balneotherapy, natural therapeutic factors,

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Mud therapy and skin microbiome: a review

Cited by 23 publications

References 67 publications

The Effects of Lakitelek Thermal Water and Tap Water on Skin Microbiome, a Randomized Control Pilot Study

The Effects of Lakitelek Thermal Water and Tap Water on Skin Microbiome, a Randomized Control Pilot Study

To treat or not to treat? Misbeliefs in spa water disinfection

Mud therapy and rehabilitation - scientific relevance in the last six years (2015 – 2020) Systematic literature review and meta-analysis based on the PRISMA paradigm

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