Müller glial cells contribute to dim light vision in the spectacled caiman ( Caiman crocodilus fuscus ): Analysis of retinal light transmission

Agte, Silke; Savvinov, Alexey; Karl, Anett; Zayas‐Santiago, Astrid; Ulbricht, Elke; Makarov, Vladimir I.; Reichenbach, Andreas; Bringmann, Andreas; Skatchkov, Serguei N.

doi:10.1016/j.exer.2018.05.009

Cited by 20 publications

(8 citation statements)

References 35 publications

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“…Changes of such an index have already been reported after refractive surgery [41-44]. For that reason, the Hydra-OCT could contribute new insights into the state of tissue hydration [45], the behavior of multicellular tumor spheroids [46], age-related changes of the lens [47], characteristics of light transmission in Müller glial cells [48] and crystalline cones [49]. A previous report showed that different OCT devices may not be used interchangeably because higher choroidal thickness values were observed in SS-OCT compared to SD-OCT [50].…”

Section: Discussionmentioning

confidence: 99%

Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

et al. 2020

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Purpose: To evaluate the feasibility and safety of a coaxial dual-wavelength optical coherence tomography (OCT) device (marked as Hydra-OCT). Methods: Healthy participants without ocular pathology underwent retinal imaging using the Hydra-OCT allowing for simultaneous measurement of retinal scanning of 840 and 1,072 nm wavelength. Before and after measurement, best-corrected visual acuity and patients’ comfort were assessed. Representative OCT images from both wavelengths were compared by 5 independent graders using a subjective grading scheme. Results: A total of 30 eyes of 30 participants (8 females and 22 males) with a mean age of 26.5 years (range from 19 to 55 years) were included. Dual-wavelength image acquisition was made possible in each subject. The participant’s effort and comfort assessment using the Hydra-OCT imaging revealed an equivalent value as compared to the commercially available OCT machine. No adverse events were reported, and visual acuity was not altered by the Hydra-OCT. Imaging between the systems was comparable. Conclusions: This study provides evidence for the feasibility and safety of a coaxial dual-wavelength OCT imaging method under real-life conditions. The novel Hydra-OCT imaging device may offer additional insights into the pathology of retinal and choroidal diseases.

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Section: Discussionmentioning

confidence: 99%

Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

et al. 2020

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“…Crystallins have been found inside rat Muller cells and photoreceptors (Zayas-Santiago et al, 2018) [11]. Müller cells have been described as living light guides in the retina, which help to trap, hold, and conduct light from their endfeet to the photoreceptors (Franze et al, 2007; Reichenbach and Bringmann, 2010; Agte et al, 2011, Reichenbach and Bringmann, 2013; Agte et al, 2018; Karl et al; 2018) [80,81,82,83,84,85]. Crystallins provide a possible mechanism for creating an ideal refractive medium for light transport.…”

Section: Methods For Reducing Light Scatteringmentioning

confidence: 99%

Tissue Transparency In Vivo

et al. 2019

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In vivo tissue transparency in the visible light spectrum is beneficial for many research applications that use optical methods, whether it involves in vivo optical imaging of cells or their activity, or optical intervention to affect cells or their activity deep inside tissues, such as brain tissue. The classical view is that a tissue is transparent if it neither absorbs nor scatters light, and thus absorption and scattering are the key elements to be controlled to reach the necessary transparency. This review focuses on the latest genetic and chemical approaches for the decoloration of tissue pigments to reduce visible light absorption and the methods to reduce scattering in live tissues. We also discuss the possible molecules involved in transparency.

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“…We also report a detailed theoretical analysis of the presently obtained results. Our novel findings may be used to explain the mechanism of light propagation along the intermediate filaments that are packed inside retinal Müller cells 22,23,31,32 and conduct light against the laws of classic optics 22,23,31,32 . Finally, our results are very promising for a wide range of future applications.…”

Section: Introductionmentioning

confidence: 94%

Macro-scale transport of the excitation energy along a metal nanotrack: exciton-plasmon energy transfer mechanism

Khmelinskii

Skatchkov

Makarov

2019

Sci Rep

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Presently we report (i) excited state (exciton) propagation in a metal nanotrack over macroscopic distances, along with (ii) energy transfer from the nanotrack to adsorbed dye molecules. We measured the rates of both of these processes. We concluded that the effective speed of exciton propagation along the nanotrack is about 8 × 107 cm/s, much lower than the surface plasmon propagation speed of 1.4 × 1010 cm/s. We report that the transmitted energy yield depends on the nanotrack length, with the energy emitted from the surface much lower than the transmitted energy, i.e. the excited nanotrack mainly emits in its end zone. Our model thus assumes that the limiting step in the exciton propagation is the energy transfer between the originally prepared excitons and surface plasmons, with the rate constant of about 5.7 × 107 s−1. We also conclude that the energy transfer between the nanotrack and the adsorbed dye is limited by the excited-state lifetime in the nanotrack. Indeed, the measured characteristic buildup time of the dye emission is much longer than the characteristic energy transfer time to the dye of 81 ns, and thus must be determined by the excited state lifetime in the nanotrack. Indeed, the latter is very close to the characteristic buildup time of the dye emission. The data obtained are novel and very promising for a broad range of future applications.

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Müller glial cells contribute to dim light vision in the spectacled caiman ( Caiman crocodilus fuscus ): Analysis of retinal light transmission

Cited by 20 publications

References 35 publications

Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

Feasibility and Safety of a Coaxial Dual-Wavelength Optical Coherence Tomography Apparatus

Tissue Transparency In Vivo

Macro-scale transport of the excitation energy along a metal nanotrack: exciton-plasmon energy transfer mechanism

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