Mullerian Adenosarcoma of the Uterine Cervix in an Adolescent Girl

Büyükkurt, Selim; Guzel, AB; Gümürdülü, Derya; Ma, Vardar; Zeren, Handan; Sucu, Mete

doi:10.1016/j.jpag.2009.05.008

Cited by 12 publications

(6 citation statements)

References 5 publications

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“…Some authors claimed that FSS should not be a preferred approach because of its high risk of recurrence . Alternatively, some authors have reported that local tumor excision may been curative in some cases . In this study, FSS was performed in four patients with cervical adenosarcoma and five with uterine adenosarcoma.…”

Section: Discussionmentioning

confidence: 91%

“…A literature search was performed via PubMed, EMBASE and Web of Science. A total of 16 and 13 cases of cervical and uterine adenosarcoma, respectively, were included . One case (case 13) was excluded from the analysis as a result of being lost to follow‐up.…”

Section: Resultsmentioning

confidence: 99%

“…The majority of the guidance regarding the management of cervical adenosarcoma is extrapolated from the experience managing uterine adenosarcoma. Surgical procedures, including excisional biopsy, tumor resection, conization, trachelectomy, hysterectomy, TH, and radical hysterectomy, have been reported . To the authors’ knowledge, there were three relatively larger studies regarding the management of cervical adenosarcoma.…”

Section: Discussionmentioning

confidence: 99%

“…Surgery is the mainstay of treatment for adenosarcomas . However, the best surgery procedure and whether fertility‐sparing surgery (FSS) can be used in cervical and uterine adenosarcoma remain controversial .…”

Section: Introductionmentioning

confidence: 99%

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Uterine and Cervical Adenosarcoma: A Retrospective Study of Overall Oncologic Outcomes and Fertility Preservation in Early-Stage Disease

Yuan

Cao

et al. 2019

The Oncologist

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Background The management of adenosarcoma is based on the limited available data. This study aimed to explore the characteristics and oncologic outcomes of patients with uterine and cervical adenosarcoma. Materials and Methods A total of 21 and 32 cases of cervical and uterine adenosarcoma, respectively, were retrospectively reviewed in Peking Union Medical College Hospital between April 2006 and March 2019. Results The median follow‐up time was 37.5 months (range, 1–153 months). The disease progression rate (DPR) was significantly higher in patients with uterine adenosarcoma compared with those with cervical adenosarcoma (28.1% vs. 4.8%). The curve of progression‐free survival significantly differed. For those with cervical adenosarcoma, the presence of a tumor stalk was a protective factor, whereas heterologous elements (HE) presented a risk factor for disease progression. For those with uterine adenosarcoma, the presence of a tumor stalk was an independent protective factor, whereas lymphovascular space invasion (LVSI) was an independent risk factor for disease progression. Moreover, HE was an independent risk factor for mortality. Fertility‐sparing surgery (FSS) was performed in four and five patients with cervical and uterine adenosarcoma, respectively. Regarding FSS, combined with cases in previous studies, the DPR of patients with uterine adenosarcoma was relatively higher compared with those with cervical adenosarcoma. Conclusion We found that cervical adenosarcoma had a better prognosis than uterine adenosarcoma. The presence of a tumor stalk was a protective factor, whereas HE and LVSI were risk factors for prognosis. For those with uterine adenosarcoma, if FSS was administered, robust evaluation would be necessary. The small sample size limits the ability to make any strong conclusions about FSS. Implications for Practice Uterine cervical adenosarcoma had a better prognosis than uterine adenosarcoma. For patients with cervical adenosarcoma, the presence of a tumor stalk was a protective factor and the presence of heterologous elements (HE) was a risk factor for disease progression. For those with uterine adenosarcoma, the presence of a tumor stalk was a protective factor and lymphovascular space invasion was a risk factor for disease progression. Moreover, HE was a risk factor for mortality. Regarding fertility‐sparing surgery (FSS), the disease progression rate was higher in patients with uterine adenosarcoma compared with those with cervical adenosarcoma. For patients with uterine adenosarcoma, if FSS was administered, hysteroscopy and robust imaging evaluation would be necessary.

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Section: Discussionmentioning

confidence: 91%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Uterine and Cervical Adenosarcoma: A Retrospective Study of Overall Oncologic Outcomes and Fertility Preservation in Early-Stage Disease

Yuan

Cao

et al. 2019

The Oncologist

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“…[3][4][5] From review of literature, our case is the fourth documented case of breast metastasis from PFTC, with previous cases reported by Fishman et al in 1994, Papakonstatinou et al in 2009, and Buyukkurt et al also in 2009. 3,6,7 All reported cases of PFTC with breast metastasis vary in their presentation, with the unifying factor being advanced stage at diagnosis.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Fallopian Tube Metastasis Presenting as a Solitary Breast Mass

Sharma

Padilla

Marji

et al. 2023

Indian J Radiol Imaging

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Metastases to the breast from a nonmammary primary are rare. Primary fallopian tube carcinoma is one of the rarest malignancies of the female genital tract. Therefore, breast metastases from primary fallopian tube carcinoma are considered extremely rare.In this article, we shared the case of serous carcinoma of fallopian tube with metastasis to an intramammary lymph node, presenting as a solitary breast mass. On initial staging 18F-fluorodeoxyglucose (FDG) positron emission tomography/computed tomography for this patient with serous carcinoma of fallopian tube, a solitary FDG avid breast mass was found, along with FDG avid multistation nodes. The breast mass was evaluated with diagnostic mammogram and ultrasound and eventually biopsy of this mass revealed metastatic lymph node from carcinoma of fallopian tube origin.

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Uterine Sarcomas and Atypical Smooth-Muscle Tumors: Clinic, Diagnostics and Appropriate Surgical Therapy

Köhler

Zygmunt

2017

Hysterectomy

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Mullerian Adenosarcoma of the Uterine Cervix in an Adolescent Girl

Cited by 12 publications

References 5 publications

Uterine and Cervical Adenosarcoma: A Retrospective Study of Overall Oncologic Outcomes and Fertility Preservation in Early-Stage Disease

Uterine and Cervical Adenosarcoma: A Retrospective Study of Overall Oncologic Outcomes and Fertility Preservation in Early-Stage Disease

A Rare Case of Fallopian Tube Metastasis Presenting as a Solitary Breast Mass

Uterine Sarcomas and Atypical Smooth-Muscle Tumors: Clinic, Diagnostics and Appropriate Surgical Therapy

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