Manufacturing knowledge (MK) is enjoying a ''new golden age'' in the academic domain, marked by vast reuse to support product-related production problems (PPs) solving decision making for manufacturing enterprises in the industry sector. However, the practice of MK reuse and research is fragmented and insufficient, which cannot be mature to provide a systemic solution for that a decision-maker has to consider the involving issues: how MK can be used earlier and rightly; what kind of practical problems can be solved? In order to answer those interconnecting issues, this paper firstly proposes a connectivism framework to clarify the compressive relationship of problem-to-problem, knowledge-to-knowledge and problem-to-knowledge with knowledge integration, knowledge matching, and problem-solving layers. Then, based on the framework, an ontology-based MK graph (MKG) is constructed with a unified MK-filter to collect and integrate multifactor and multilevel MK, and a graph-oriented meta-knowledge model (MKM) is proposed to represent the details between the knowledge entities (i.e., concept and instance), which also shows the contribution to knowledge reasoning. After that, driven by a structure temporal query (i.e., 5W2H), a semantics-based knowledge computation is developed to compute the intrinsic term similarity (IS) and relational term similarity (RS) between two knowledge entities in the MKG. Finally, a case study is taken to demonstrate the effectiveness and performance of the proposed methods. INDEX TERMS Production problems (PPs), manufacturing knowledge (MK), manufacturing knowledge graph (MKG). The associate editor coordinating the review of this manuscript and approving it for publication was Shih-Wei Lin. reuse percentage averages a 28% for manufacturing application [3].The Defense Acquisition University(2011) proposes that the acquisition, operation and support of product could account for 60-80% of the product life cycle cost [4]. These claims highlight that the marginal value of more MK reused by enterprises is the decrease in production cost of product lifecycle, and the increase in effective production time, efficiency and profit permitted by a smaller amount of production problem-solving time. However, from the angle of systematic view of PPs solving with MK, a lack of connective vision among problem solvers has limited the availability of industry-mature solutions. So, the question still needs to be answered: how to use MK, timely, in the product life cycle, to provide a more mature and accurate solution of decision-making for problems solving? While, previous researches have tried to identify the chance in exploring the knowledge reuse for