Multi-band SWIFT enables quiet and artefact-free EEG-fMRI and awake fMRI studies in rat

Paasonen, Jaakko; Laakso, Hanne; Pirttimäki, Tiina; Stenroos, Petteri; Salo, Raimo A.; Zhurakovskaya, Ekaterina; Lehto, Lauri J.; Tanila, Heikki; Michaeli, Shalom; Idiyatullin, Djaudat; Mangia, Silvia; Gröhn, Olli

doi:10.1016/j.neuroimage.2019.116338

Cited by 34 publications

(59 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Lastly, we found out that simple rigid transformation was sufficient for motion correction purposes and scaling factors were not required. This minimized potential scaling-induced artefacts during motion correction but also supported the concept that MB-SWIFT images are not affected by the body movement-induced field distortions in contrast to traditional EPI 17 .…”

Section: Spontaneous Behavior and Head Movementsupporting

confidence: 67%

“…Habituation was done in a home-made wooden box (90 x 40 x 30 cm 3 ), equipped with the imaging holder, a loudspeaker (BG-17, Visaton, Haan, Germany), and an infrared web camera. The recording and playback (Servo 200, Samson, Hicksville, NY, USA) of scanner noise was done as described previously 14,17 . Light maintenance anesthesia, either isoflurane (1.3-1.8%) or sevoflurane (1.8-3.0%; Sevorane, ABBVIE Oy, Helsinki, Finland), was used while inserting ear plugs and harness, while taking blood samples, and while the rat was positioned to or removed from the MRI holder.…”

Section: Habituation Protocol For Head-fixed Awake Imagingmentioning

confidence: 99%

“…MRI parameters were similar as described earlier 17 Prior to MRI, the rat was prepared and positioned to the MRI holder as during habituation, except the MRI surface loop coil was placed around the head implant below the head-fixation pins and a pneumatic breathing sensor pad (Model 1025, Small Animal Instruments Inc., New York, NY, USA) was placed inside the harness to follow breathing rate. An MRI-compatible video camera with infrared light (12M-i, MRC Systems GmbH, Heidelberg, Germany) was placed front side of the rat to record behavior.…”

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

“…While studying behavior with fMRI, body movement restriction and loud acoustic noise are the greatest confounders in both animal and human applications. To overcome these and several other limitations imposed by the standard commonly utilized echo planar imaging (EPI) fMRI, we introduced a novel 3D zero echo time fMRI approach based on the Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) technique [15][16][17] . MB-SWIFT fMRI does not rely on the blood oxygenation level dependent (BOLD) contrast, but appears to be sensitive to blood inflow 16 and provides even better functional contrast as compared to spin-echo EPI 16 .…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI

Paasonen

Stenroos

Laakso

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

Understanding the link between the brain activity and behavior is a key challenge in modern neuroscience. Behavioral neuroscience, however, lacks tools to record whole-brain activity in complex behavioral settings. Here we demonstrate that a novel Multi-Band SWeep Imaging with Fourier Transformation (MB-SWIFT) functional magnetic resonance imaging (fMRI) approach enables whole-brain studies in spontaneously behaving head-fixed rats. First, we show anatomically relevant functional parcellation. Second, we show sensory, motor, exploration, and stress-related brain activity in relevant networks during corresponding spontaneous behavior. Third, we show odor-induced activation of olfactory system with high correlation between the fMRI and behavioral responses. We conclude that the applied methodology enables novel behavioral study designs in rodents focusing on tasks, cognition, emotions, physical exercise, and social interaction. Importantly, novel zero echo time and large bandwidth approaches, such as MB-SWIFT, can be applied for human behavioral studies, allowing more freedom as body movement is dramatically less restricting factor.

show abstract

Section: Spontaneous Behavior and Head Movementsupporting

confidence: 67%

Section: Habituation Protocol For Head-fixed Awake Imagingmentioning

confidence: 99%

Section: Magnetic Resonance Imagingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI

Paasonen

Stenroos

Laakso

et al. 2021

Preprint

Self Cite

View full text Add to dashboard Cite

show abstract

“…While spin-echo EPI is less vulnerable for susceptibility artefacts, the application can be limited due to the slow acquisition time and heating 51 . Alternatively, the recent development of zero echo time fMRI techniques (e.g., Multi-band SWIFT) 52,53 or Point-spread-function-based phase distortion correction 54 would be promising in terms of reducing susceptibility-induced artifacts for a metallic electrode.…”

Section: Discussionmentioning

confidence: 99%

Multivariate pattern classification on BOLD activation pattern induced by deep brain stimulation in motor, associative, and limbic brain networks

Cho

Min

et al. 2020

Sci Rep

View full text Add to dashboard Cite

Deep brain stimulation (DBS) has been shown to be an effective treatment for movement disorders and it is now being extended to the treatment of psychiatric disorders. Functional magnetic resonance imaging (fMRI) studies indicate that DBS stimulation targets dependent brain network effects, in networks that respond to stimulation. Characterizing these patterns is crucial for linking DBS-induced therapeutic and adverse effects. Conventional DBS-fMRI, however, lacks the sensitivity needed for decoding multidimensional information such as spatially diffuse patterns. We report here on the use of a multivariate pattern analysis (MVPA) to demonstrate that stimulation of three DBS targets (STN, subthalamic nucleus; GPi, globus pallidus internus; NAc, nucleus accumbens) evoked a sufficiently distinctive blood-oxygen-level-dependent (BOLD) activation in swine brain. The findings indicate that STN and GPi evoke a similar motor network pattern, while NAc shows a districted associative and limbic pattern. The findings show that MVPA could be effectively applied to overlapping or sparse BOLD patterns which are often found in DBS. Future applications are expected employ MVPA fMRI to identify the proper stimulation target dependent brain circuitry for a DBS outcome.

show abstract

Sweep Imaging with Fourier Transformation (SWIFT)

Idiyatullin¹

2022

Magnetic Resonance Microscopy

View full text Add to dashboard Cite

Multi-band SWIFT enables quiet and artefact-free EEG-fMRI and awake fMRI studies in rat

Cited by 34 publications

References 56 publications

Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI

Whole-brain studies of spontaneous behavior in head-fixed rats enabled by zero echo time MB-SWIFT fMRI

Multivariate pattern classification on BOLD activation pattern induced by deep brain stimulation in motor, associative, and limbic brain networks

Sweep Imaging with Fourier Transformation (SWIFT)

Contact Info

Product

Resources

About