Multi-center living liver donor quality of life survey up to 20 years after donor hepatectomy and association with surgical outcomes

Andaçoğlu, Oya; Sabisch, Eva; Malamutmann, Eugen; Özbek, Umut; Emre, Anilalp; Tokat, Yaman; Oezcelik, Arzu

doi:10.1016/j.hpb.2022.06.007

Cited by 1 publication

(2 citation statements)

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“…This finding aligns with the literature, as evidenced by a systematic review reporting a prevalence rate of post-donation regret among LLDs ranging from 0% to 11.4% [8]. However, more recent research conducted in Germany and Turkey, encompassing a follow-up period of up to 20 years after donation, revealed a regret prevalence rate of 27.5% [44]. Furthermore, a study in Egypt found that 67% of LLDs would not donate again [45].…”

Section: Discussionsupporting

confidence: 87%

“…Furthermore, a study in Egypt found that 67% of LLDs would not donate again [45]. Noteworthy distinctions between these studies and our own lie in the scope of donor-recipient relationships examined, with our study focusing on second-degree relatives, while the aforementioned studies encompassed relatives up to the fourth degree and non-relatives [44,45]. This may have contributed to the prevalence of regret.…”

Section: Discussionmentioning

confidence: 85%

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Post-Donation Regret and Anxiety Among Family Living Liver Donors: The Mediating Roles of Family Relationships and Sense of Mastery

Lee,

Koh,

2024

Ann Transplant

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Background:Post-donation regret in family living liver donors can impact their mental well-being. This study examined whether the relationship between post-donation regret and anxiety is mediated by family relationships and a sense of mastery. Material/Methods:We conducted a secondary analysis of de-identified cross-sectional data from a prior study that included 124 living liver donors. These donors underwent partial hepatectomy between January 2011 and March 2021 at a tertiary hospital in Seoul, South Korea. The data included demographic and clinical characteristics, along with the results from administering the following measures: the Post-Donation Regret Scale, Family Relationships Index, Pearlin Mastery Scale, and the Generalized Anxiety Disorder-2 scale. Results:Among family living liver donors, 5.6% had anxiety after donation. The total effect of post-donation regret on anxiety was significant (B=0.41, p<0.05). However, the direct effect of regret on anxiety was not significant (B=-0.05, p=0.733). Post-donation regret had indirect effects on anxiety, solely through family relationships (B=0.329, 95% CI=0.130, 0.563) and sequentially through family relationships and mastery (B=0.088, 95% CI=0.008, 0.232), even after controlling for sex, age, postoperative complications, years since donation, and recipient's death. In addition, postoperative complication was a predictor of anxiety (B=0.64, p<0.05). Conclusions:Providing family-centered and mastery-enhancing interventions may help alleviate the anxiety of family living liver donors.

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Section: Discussionsupporting

confidence: 87%