Multi-center randomized trial on the impact of “CONFIDENCE” communication program aimed at evaluating therapy adherence of patients with registered myocardial infarction who underwent successful revascularization by stenting or thrombolysis after discharg

Abstract

<p><strong>Aim.</strong> The article looks at the effect of the program "Confidence" to increase the proportion of patients’ therapy in patients with coronary heart disease for two years after successful revascularization using thrombolytic or stenting of the coronary arteries on the myocardial infarction.<br /><strong>Methods.</strong> This is a prospective, randomized, controlled, parallel-group trial including 4.000 patients. They will be divided into two groups: patients receiving standard outpatient observation (n=2000) and those enrolled for the program "Confidence" (n=2000). The total duration is 24 months. The trial will take place in two stages. In the first stage (0-12 months) the impact of the program "Confidence" on therapy adherence and outcomes of cardiovascular diseases will be assessed. In the second stage (after the change of groups in 12 months, 12-24 months) the effect of changing the way to remind patients of therapy adherence will be evaluated.<br /><strong>Conclusion.</strong> The trial was designed in such a way as to show that the proposed program "Confidence" increases the proportion of patients who adhere to therapy in the cohort of those with coronary heart disease for two years after successful revascularization by using thrombolytic or stenting of the coronary arteries against the background of myocardial infarction.</p><p>Received 13 February 2017. Accepted 9 March 2017.</p><p><strong>Financing:</strong> KRKA company’s grant. Sponsorship had no effect on data acquisition, analysis and interpretation.</p><p><strong>Conflict of interest:</strong> Kretov E.I. served as executive editor of “Endovascular surgery” section. All other authors declare no conflict of interest.</p><p><strong>Author contributions</strong><br />Study conception and design: Kretov E.I., Grazhdankin I.O., Baystrukov V.I., Zubarev D.D. <br />Statistical data processing: Krestyaninov O.V., Kozyr K.V., Obedinskiy A.A., Prokhorikhin A.A.<br />Drafting the article: Tarkova A.R., Anisimova V.D.<br />Critical revision: Tarkova A.R., Anisimova V.D., Kretov E.I.</p>