2020
DOI: 10.1016/j.talanta.2020.121326
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Multi-class analysis of 46 antimicrobial drug residues in pond water using UHPLC-Orbitrap-HRMS and application to freshwater ponds in Flanders, Belgium

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Cited by 39 publications
(29 citation statements)
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“…No study has been found in the literature reporting on nitrofurantoin levels in sewage water. Goessens et al published a study on antimicrobial residues in pond water in Flanders, Belgium, where nitrofurantoin was below the limit of detection (LOD) in all samples [36].…”
Section: Detecting the Presence Of Selected Antibiotics In Water Samplesmentioning
confidence: 99%
“…No study has been found in the literature reporting on nitrofurantoin levels in sewage water. Goessens et al published a study on antimicrobial residues in pond water in Flanders, Belgium, where nitrofurantoin was below the limit of detection (LOD) in all samples [36].…”
Section: Detecting the Presence Of Selected Antibiotics In Water Samplesmentioning
confidence: 99%
“…Furthermore, SPE can be installed on-line with a chromatographic system and automated, which allows high throughput analysis; this is the case for some studies reported in Table 2 [47]. Oasis HLB™ are the most used cartridges in the reported studies, as they are suitable for the simultaneous extraction of compounds from various families: sulfonamides (SMX, SDZ, SMZ), tetracyclines (TET, OTC), quinolones (OFLO, FLU, CPIX), macrolides (ERY), nitrofurans and phenicols (FF) [15,23,47]. Apart from SPE-based approach, various sample preparation processes have been reported, including liquidliquid extraction (LLE) with or without sonication or microwave assistance (Norambuena et al, 2013;Prat et al, 2006).…”
Section: Methods For Characterization Of Drugs Used In Fish Farmingmentioning
confidence: 99%
“…Hybrid mass spectrometers associating a quadrupole, a collision cell, and an ion trap have been also reported; their principle of operation is quite similar to that of TQs except that the ion trap permits ion accumulation before detection [47,49]. Among all the studies listed in Table 2, only that by Goessens et al refers to a high-resolution mass spectrometer (Orbitrap™), which has been employed to analyze 46 antimicrobial drug residues including sulfonamides, tetracyclines, quinolones, macrolides, nitrofurans and phenicols in aquatic matrices [23]. Since it allows the differentiation of isobaric ions, high-resolution mass spectrometry (HRMS) constitutes a tool of choice for structural elucidation of metabolites and by-products; it also significantly reduces interferences during routine analysis of very complex matrices.…”
Section: Methods For Characterization Of Drugs Used In Fish Farmingmentioning
confidence: 99%
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