Multi–Detector Row CT Colonography: Effect of Collimation, Pitch, and Orientation on Polyp Detection in a Human Colectomy Specimen

Taylor, Stuart A.; Halligan, Steve; Bartram, Clive I.; Morgan, P R; Talbot, Ian C.; Fry, Nicola; Saunders, Brian P.; Khosraviani, K; Atkin, Wendy

doi:10.1148/radiol.2291020561

Cited by 60 publications

(18 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Their studies focused on finding the imaging effect of collimation, tube current (pitch) and orientation when they analysed different sizes and types of polyps. Similar studies were performed by Taylor et al [49] and Springer et al [50]. Using a different approach, Whithing et al [51] constructed an air filled acrylic cylinder where polyps of different sizes were attached on the 3 inner side of the acrylic tube and they applied the developed phantom to evaluate the artefacts generated by the collimation and the tube current.…”

Section: Introductionmentioning

confidence: 89%

“…Cohen [43] indicates in his paper that the risk of inducing cancer in patients is significantly lowered when they are subjected to low-level radiation exposure and an important number of studies were carried out in order to identify the minimal level of radiation dose that can be used in CTC but without a negative impact on the detection of colorectal polyps [41,[44][45][46]. The identification of the optimal scanning parameters (collimation, slice thickness, table speed, reconstruction interval) is a difficult problem and this procedure is applied on synthetic phantoms that are designed to accurately model the human body [47][48][49][50][51][52][53][54][55][56][57][58]. In this sense, Beaulieu et al [47] used spherical plastic beads to model polyps while Dachman et al [48] created false polyps in a pig colon by puckering the mucosa of the colon.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Development of a synthetic phantom for the selection of optimal scanning parameters in CAD–CT colonography

Chowdhury

Whelan

Ghita

et al. 2007

Medical Engineering & Physics

View full text Add to dashboard Cite

The aim of this paper is to present the development of a synthetic phantom that can be used for the selection of optimal scanning parameters in Computed Tomography (CT) colonography. In this paper we attempt to evaluate the influence of the main scanning parameters including slice thickness, reconstruction interval, field of view, table speed and radiation dose on the overall performance of a Computer Aided Detection (CAD)-CTC system. From these parameters the radiation dose received a special attention, as the major problem associated with CTC is the patient exposure to significant levels of ionising radiation. To examine the influence of the scanning parameters we performed 51 CT scans where the spread of scanning parameters was divided into seven different protocols. A large number of experimental tests were performed and the results analysed. The results show that automatic polyp detection is feasible even in cases when the CAD-CTC system was applied to low dose CT data acquired with the following protocol: 13mAs/rotation with collimation of 1.5x16mm, slice thickness of 3.0mm, reconstruction interval of 1.5mm, table speed Preprint submitted to Elsevier Science 13 September 2006of 30mm per rotation. The CT phantom data acquired using this protocol was analysed by an automated CAD-CTC system and the experimental results indicate that our system identified all clinically significant polyps (i.e. larger than 5mm).

show abstract

Section: Introductionmentioning

confidence: 89%

Section: Introductionmentioning

confidence: 99%

Development of a synthetic phantom for the selection of optimal scanning parameters in CAD–CT colonography

Chowdhury

Whelan

Ghita

et al. 2007

Medical Engineering & Physics

View full text Add to dashboard Cite

show abstract

“…A high pitch value decreases the scanning time, a lower tube current reduces the radiation exposure, and a smaller slice thickness improves image quality. A study found that polyps 5-mm or larger in size could be detected with 1.25-mm collimation, pitch of 6, and 60 mA tube current (36). The same study found that the optimal settings for detecting polyps less than 5-mm in size were 1.25-mm collimation, pitch of 3, and 150mA tube current (36).…”

Section: Optimal Settingsmentioning

confidence: 96%

“…A study found that polyps 5-mm or larger in size could be detected with 1.25-mm collimation, pitch of 6, and 60 mA tube current (36). The same study found that the optimal settings for detecting polyps less than 5-mm in size were 1.25-mm collimation, pitch of 3, and 150mA tube current (36). Studies are also being conducted to reduce radiation exposure while still maintaining high sensitivity and specificity values (37).…”

Section: Optimal Settingsmentioning

confidence: 99%

Current Status of CT Colonography

Frentz¹,

Summers²

2006

Academic Radiology

View full text Add to dashboard Cite

In 2006, over 55,000 Americans are expected to die of colorectal cancer (CRC) (1). It is estimated that there is over a 5% chance that an American will develop CRC in their lifetime and over a 2% chance that an American will die from CRC (2). Fortunately, in most cases, controlling CRC is possible with the proper screening methods and the subsequent removal of suspicious polyps, adenomas, and carcinomas. If CRC is detected at an early stage, the 5-year survival rate is 90%. Unfortunately, less than 40% of colorectal cancers are detected at an early stage. Once the cancer has developed distant metastases, the 5-year survival rate is less than 10% (2).From 1998 to 2002, the incidence rate of CRC decreased by 1.8% per year, which is believed to have occurred due to increased awareness of the importance of CRC screening and consequent polyp removal (2). However, CRC is still predicted to cause about 10% of all cancer-related deaths in the United States in 2006. Relatively accurate screening methods are available to patients, but patient participation in CRC screening continues to be low. Computed tomography colonography (CTC) is a relatively new screening technology that aims to achieve a high patient acceptance, diagnostic accuracy, and screening effectiveness thereby decreasing mortality rates due to CRC.

show abstract

“…MDCT has several technical advantages over single-detector CT, including faster imaging times, reduced exposure to radiation and acquisition of multiple thin sections with nearly isotropic voxels. [2,3,7,11,22,23,[43][44][45][46] Moreover, motion artifacts from respiration and peristalsis are decreased or eliminated with MDCT. [3] Thin sections are a prerequisite for high-quality multiplanar reformations (MPR) and 3D reconstructions.…”

Section: Data Acquisitionmentioning

confidence: 99%