“…Tel. : made to define a framework, including hardware and software features, for realizing programmable microfluidic systems able to execute a large number of different elementary analyses within a single device [6][7][8][9]4]. A number of problems have prevented this very ambitious goal to be reached; however recently the introduction of an emerging approach denoted as droplet-based microfluidics [3,10], first, and the introduction of the innovative concept of bubble logic [2] later, have shown that the design of microfluidic networks aimed at supporting flexible, low-cost and scalable programmable microfluidic systems is feasible.…”