Abstract:Purpose: To compare different multi-echo combination methods for MRI quantitative susceptibility mapping (QSM), aiming to elucidate, given the current lack of consensus, how to optimally combine multi-echo gradient-recalled echo (GRE) signal phase information, either before or after applying Laplacian-base methods (LBMs) for phase unwrapping or background field removal.
Methods: Multi-echo GRE data were simulated in a numerical head phantom, and multi-echo GRE images were acquired at 3 T in 10 healthy voluntee… Show more
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