Multi-energy spectral CT: adding value in emergency body imaging

Punjabi, Gopal

doi:10.1007/s10140-017-1569-4

Cited by 8 publications

(7 citation statements)

References 22 publications

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“…FORCE dual-energy CT represents an extremely advanced spiral CT, with high density and time resolution (24,25). In addition to two- and three-dimensional recombination like ordinary spiral CT, its unique pure-spectrum photon energy purification technology enables dual-energy imaging, which allows for more accurate energy-and-material separation (10). Using spectral purification technology, the radiation dose can be effectively reduced while meeting the diagnostic requirements.…”

Section: Discussionmentioning

confidence: 99%

“…Dual-energy CT iodine quantification has been applied in the differential diagnosis of benign and malignant renal tumors for tumor classification, and the majority of the machines are less advanced dual-energy CT (10–12). FORCE dual-energy CT allows pathological grading of renal tumors by quantitative determination of substance and energy separately.…”

Section: Discussionmentioning

confidence: 99%

“…FORCE dual-energy CT can provide higher accuracy when reflecting the renal cancer microstructure, with better diagnostic value compared with conventional enhanced CT. The dual-energy parameters have certain tissue specificity, which can accurately reflect the tissue composition (10). However, the iodine map could accurately extract the iodine representing the enhancement degree, so as to objectively and accurately reflect the blood supply and microvessels for the tumors (19).…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, with the rapid development of energy spectrum CT imaging technology, CT has changed from single-parameter imaging to multi-parameter imaging, and from reflecting the gross morphology to microscopic features of lesions, with tissue specificity (10,11). FORCE CT pure-spectrum photon technology enables precise separation of multi-substance components, which can automatically generate iodine- and single-energy-images, and the following parameters can be obtained: Virtual network computing (VNC) CT values, single-energy CT values, mixed energy CT values, iodine concentration and normalized iodine concentration (NIC) of the regions of interest (12).…”

Section: Introductionmentioning

confidence: 99%

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FORCE dual‑energy CT in pathological grading of clear cell renal cell carcinoma

Zhang

Wang

et al. 2019

Oncol Lett

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The aim of the present study was to examine the value of FORCE dual-energy CT in grading the clear cell renal cell carcinoma (ccRCC). A total of 35 cases of ccRCC were included. Hematoxylin and eosin staining was performed, and the cases were divided into low- (Fuhrman I–II) and high-grade (Fuhrman III–IV) groups. FORCE dual-energy CT parameters, including virtual network computing CT value (VNCV), iodine overlay value (IOV), mixed energy CT value (MEV), iodine concentration (IC), normalized iodine concentration (NIC), NIC based on aorta (NICA), NIC based on cortex (NICC) and NIC based on medulla (NICM), were analyzed and compared. Receiver operating characteristic analysis was also performed. There were significant differences in the arterial phase IOV, MEV and IC, and the venous phase IOV and IC between the low- and high-grade groups. No significant differences were observed in VNCV and MEV between the low -and high-grade groups in the venous phase. Significant differences were observed in the NICA and NICC between these two groups, however no difference was observed in NICM. There were significant differences in the tumor CT values for the arterial phase at the 40, 60, 80 and 100 kiloelectron volt (keV) between the low- and high-grade groups, while no significant differences were observed at the 120–140 keV levels. The k-slope for the low-grade group was significantly higher than the high-grade group. In addition, the area under curve for the arterial phase IOV, arterial phase MEV, arterial phase IC, aortic NIC, cortical NIC, venous phase IOV, venous phase IC and curve slope K of mono-energy CT value suggested high value in diagnosis of low- and high-grade ccRCC cases.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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FORCE dual‑energy CT in pathological grading of clear cell renal cell carcinoma

Zhang

Wang

et al. 2019

Oncol Lett

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“…In regard to the limitations of spectral CT, it may be that performing multiple spectral reconstructions can be expected to increase the reconstruction time and expense of archiving additional images. In addition, reviewing additional images on dedicated thin client servers may increase radiologists' interpretation time [17].…”

Section: Discussionmentioning

confidence: 99%

Application of spectral CT in the diagnosis of contrast encephalopathy following carotid artery stenting: a case report

2020

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Background Contrast encephalopathy is a rare complication of carotid artery stenting (CAS). Contrast encephalopathy is a diagnosis of exclusion that often needs to be distinguished from high perfusion syndrome, cerebral haemorrhage, subarachnoid haemorrhage (SAH), cerebral infarction and so on. Case presentation In this study, we report on a 70-year-old man who was admitted to the hospital with transient ischaemic attacks presenting paroxysmal weakness of limbs in the previous 2 years. He had severe stenosis of the left internal carotid artery diagnosed by digital subtraction angiography (DSA) and underwent CAS. Two hours after the operation, the patient developed paralysis of the right upper limb, unclear speech, fever and restlessness. Emergency skull computed tomography (CT) showed swelling and a linear high-density area in the left cerebral hemisphere. To clarify the components of this high-density area in the traditional CT, the patient had spectral CT, which made the diagnosis of the leakage of contrast clear. After 1 week of supportive treatment, the patient improved. Conclusions Spectral CT can easily distinguish the components of high-density areas on traditional CT, which is haemorrhage, calcification or iodine contrast leakage. Therefore, spectral CT is worth consideration for the differential diagnosis of complications of vascular intervention.

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