The containment of the COVID-19 pandemic was significantly affected by the unbalanced distribution of emergency supplies, low coordinated transport efficiency, high costs, and the inability of nonprofit organizations to handle the emergency supplies efficiently. Based on the COVID-19 experience, in this paper, we build a cloud platform for emergency supplies distribution to reduce the asymmetry of emergency logistics information, reduce the costs, and improve the efficiency of emergency supplies distribution. Our proposed method uses a genetic algorithm with the monarch scheme to optimize the urban emergency supplies distribution. The numerical results and sensitivity analysis for a sample network indicate that using the proposed platform the integrated cost in different cities are reduced by 29.01%, 28.67%, and 22.73%, the required time in different cities are reduced by 22.98%, 26.59%, and 36.65%. The results suggest that the proposed method reduces the integrated cost and transportation time and finds the optimal distribution path.